Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610585 | 0.87 | L3MBTL1 (0.57) | ALDH1A1HPGDL3MBTL1TDP1MAOB | |
| SCHEMBL25206262 | 0.83 | ALDH1A1 (0.51) | ALDH1A1HPGDL3MBTL1TDP1MAOB | |
| SCHEMBL2742811 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HPGDL3MBTL1TDP1MAOB | |
| SCHEMBL3227770 | 0.77 | MAOB (0.45) | MAOBKMT2ASMN1; SMN2TSHRNOX1 | |
| Benzophenone SCHEMBL10489584 | 0.76 | HPGD (0.63) | ALDH1A1HPGDTDP1MAOBMEN1 | |
| SCHEMBL51623 | 0.76 | HPGD (0.63) | ALDH1A1HPGDTDP1MAOBMEN1 | |
| SCHEMBL11782996 | 0.76 | L3MBTL1 (0.53) | ALDH1A1HPGDL3MBTL1TDP1ATM | |
| SCHEMBL9620455 | 0.75 | HPGD (0.50) | ALDH1A1HPGDL3MBTL1TDP1MAOB | |
| SCHEMBL872529 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HPGDL3MBTL1TDP1MEN1 | |
| SCHEMBL28067618 | 0.74 | SMN1; SMN2 (0.55) | ALDH1A1HPGDL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127691-A1 | Process for surface functionalsation of polymeric substrates using diaryl carbenes as reactive intermediates | MOLONEY MARK GERARD (GB) | 2004-07-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127691-A1 | Process for surface functionalsation of polymeric substrates using diaryl carbenes as reactive intermediates | CYCS, CTTN, CYBB | ALDH1A1 451/4885HPGD 3187/4885L3MBTL1 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.