Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 4/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.34 |
| ▸ | LIPE | Q05469 | 5/20 | 0.33 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | P4HB | P07237 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31042930 | 0.82 | MAPT (0.45) | UCHL1 | |
| SCHEMBL18355847 | 0.81 | ALDH1A1 (0.44) | F11CXCR2LIPEDGAT1UCHL1 | |
| SCHEMBL21224382 | 0.79 | LPL (0.37) | CXCR2DGAT1UCHL1LIPG | |
| SCHEMBL24107664 | 0.78 | CHRM2 (0.36) | ROCK2CXCR2LIPEDGAT1UCHL1 | |
| SCHEMBL17967601 | 0.78 | ROCK2 (0.39) | ROCK2F11CXCR2LIPEF2 | |
| SCHEMBL31284350 | 0.78 | ALDH1A1 (0.35) | F11CXCR2LIPELIPG | |
| SCHEMBL19743759 | 0.78 | LPL (0.34) | CXCR2LIPEDGAT1LIPG | |
| SCHEMBL29179974 | 0.77 | CXCR2 (0.40) | F11CXCR2LIPEF2PRSS1 | |
| SCHEMBL25252097 | 0.75 | DGAT1 (0.34) | F11LIPEDGAT1UCHL1LIPG | |
| SCHEMBL29266820 | 0.75 | ROCK2 (0.43) | ROCK2F11CXCR2LIPEF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100173901-A1 | Substituted Heterocyclic Compounds | INCYTE CORPORATION (US) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173901-A1 | Substituted Heterocyclic Compounds | HRH4, HRH2, HRH1 | ROCK2 4661/4885F11 1227/4885CXCR2 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.