SCHEMBL3228699

SCHEMBL3228699

CCCN(CCC)CCc1ccc(OC)c(OCCc2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 1.00
EBP Q15125 1/20 1.00
TMEM97 Q5BJF2 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL467088 0.99 SIGMAR1 (1.00) SIGMAR1EBPTMEM97
Hydrochloric Acid SCHEMBL30527972 0.99 SIGMAR1 (1.00) SIGMAR1EBPTMEM97
Oxalic Acid SCHEMBL8728738 0.94 SIGMAR1 (0.89) SIGMAR1EBPTMEM97
SCHEMBL9073187 0.94 SIGMAR1 (0.88) SIGMAR1EBPTMEM97
SCHEMBL8196417 0.93 SIGMAR1 (0.86) SIGMAR1EBPTMEM97
Hydrochloric Acid SCHEMBL9077060 0.92 SIGMAR1 (0.87) SIGMAR1EBPTMEM97
SCHEMBL9076822 0.92 SIGMAR1 (0.85) SIGMAR1EBPTMEM97
Hydrochloric Acid SCHEMBL8189474 0.91 SIGMAR1 (0.86) SIGMAR1EBPTMEM97
Hydrochloric Acid SCHEMBL9077835 0.91 SIGMAR1 (0.85) SIGMAR1EBPTMEM97
Hydrochloric Acid SCHEMBL9077762 0.91 SIGMAR1 (0.85) SIGMAR1EBPTMEM97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122012182-A Method for synthesizing branched fatty acid ester of hydroxy fatty acid by taking natural oil containing hydroxy fatty acid as raw material 江南大学 2026-05-12 CN claimed
WO-2025233557-A1 SIGMA-1 RECEPTOR INHIBITING AGENTS FOR TREATING RHEUMATOID ARTHRITIS UNIVERSIDAD DE GRANADA (ES) 2025-11-13 WO claimed
CN-119818506-A Pharmaceutical composition for preventing and/or treating pain and application thereof 江苏海洋大学 2025-04-15 CN claimed
CN-118562903-B Method for preparing diglyceride oil by solvent-free enzyme method 江南大学 2025-04-11 CN claimed
CN-119776454-A Method for reducing free fatty acid by high acid value processing grease biological enzyme method 无锡蔚蓝生物科技有限公司 2025-04-08 CN claimed
CN-118562903-A Method for preparing diglyceride oil by solvent-free enzyme method 江南大学 2024-08-30 CN claimed
CN-118360349-A Preparation method and application of medium-chain fatty acid triglyceride 广东聚石科技研究院有限公司 2024-07-19 CN claimed
WO-2024105225-A1 SYNERGISTIC COMBINATIONS OF A SIGMA RECEPTOR 1 (S1R) ANTAGONIST AND A SOLUBLE EPOXIDE HYDROLASE INHIBITOR (SEHI) AND THEIR USE IN THE TREATMENT OF PAIN UNIVERSITAT DE BARCELONA (ES) 2024-05-23 WO claimed
CN-113853458-B Woven cloth, method of preparing the same, and article or garment comprising the same 尚科纺织企业工业及贸易公司 2024-04-30 CN claimed
US-20230263797-A1 Mammalian Hybrid Pre-Autophagosomal Structure HyPAS and Compositions and Methods for the Treatment of Coronavirus Infections and Related Disease States UNM RAINFOREST INNOVATIONS (US) 2023-08-24 US claimed
CN-115216497-A Preparation method of diglyceride edible oil 程秀梅 2022-10-21 CN claimed
WO-2010015040-A1 THERAPY AND PREVENTION OF TDP-43 PROTEINOPATHY POWMRI LTD (AU) 2010-02-11 WO claimed
US-6436938-B1 ADMINISTERING A SIGMA RECEPTOR LIGAND IN COMBINATION WITH AN ANTIDEPRESSANT AGENT; ESPECIALLY FOR REFRACTORY DEPRESSION PFIZER INC. 2002-08-20 US claimed
US-20020099045-A1 Combination treatment for depression PFIZER PRODUCTS INC. 2002-07-25 US claimed
EP-1224930-A1 Combination of a SR inhibitor and sigma receptor ligand in the treatment ofdepression Pfizer Products Inc. (US) 2002-07-24 EP claimed
EP-0717990-B1 COMPOSITION FOR REMEDYING DRUG DEPENDENCE TAISHO PHARMACEUTICAL CO LTD (JP) 2000-05-24 EP claimed
EP-0641766-B1 ALKOXYPHENYLALKYLAMINE DERIVATIVE TAISHO PHARMACEUTICAL CO LTD (JP) 1998-11-11 EP claimed
EP-4748441-A2 COMPOSITIONS COMPRISING ATICAPRANT Janssen Pharmaceuticals, Inc. (US) 2026-05-27 EP disclosed
WO-2002030422-A1 USE OF DEFINED SUBSTANCES THAT BIND TO THE SIGMA RECEPTOR FOR COMBATING SARCOMA AND CARCINOMA MERCK PATENT GMBH (DE) 2002-04-18 WO disclosed
EP-0717990-B1 COMPOSITION FOR REMEDYING DRUG DEPENDENCE TAISHO PHARMACEUTICAL CO LTD (JP) 2000-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020099045-A1 Combination treatment for depression HTR5A, HTR1A, OPRL1 SIGMAR1 13/4885EBP 1526/4885TMEM97 50/4885
US-20230263797-A1 Mammalian Hybrid Pre-Autophagosomal Structure HyPAS and Compositions and Methods for the Treatment of Coronavirus Infections and Related Disease States SARS1, SQSTM1, ATG4A SIGMAR1 2480/4885EBP 524/4885TMEM97 655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.