Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11690133 | 0.81 | ESR1 (0.50) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3450708 | 0.79 | ALDH1A1 (0.58) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3228726 | 0.77 | HRH4 (0.57) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9235311 | 0.76 | CDC7 (0.44) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3233802 | 0.75 | TLR8 (0.71) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL416616 | 0.74 | MEN1 (0.66) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3473227 | 0.74 | MEN1 (0.66) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL15757006 | 0.74 | AGPAT2 (0.52) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL21765569 | 0.73 | MEN1 (0.63) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL782567 | 0.73 | MEN1 (1.00) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820654-B2 | Pyrimidine compounds, process for their preparation and compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-10-26 | — | — | US | disclosed |
| US-20060084645-A1 | Novel pyrimidine compounds, process for their preparation and compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084645-A1 | Novel pyrimidine compounds, process for their preparation and compositions containing them | UMPS, DPYD, TYMS | KMT2A 4623/4885ALDH1A1 3580/4885MEN1 4470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.