SCHEMBL3229094

SCHEMBL3229094

CCCCCCCC(CCCCC)CN1CCCCC1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
ALDH1A1 P00352 1/20 0.42
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HRH3 Q9Y5N1 2/20 0.38
LTA4H P09960 1/20 0.38
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
CHRM1 P11229 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
OPRM1 P35372 1/20 0.38
DRD3 P35462 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KCNH2 Q12809 1/20 0.38
CYP2D6 P10635 1/20 0.38
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22236670 1.00 LMNA (0.43) LMNAL3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL22236667 1.00 LMNA (0.43) LMNAL3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL24404816 0.98 LMNA (0.45) LMNAL3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL23957178 0.98 LMNA (0.45) LMNAL3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL28887787 0.98 LMNA (0.45) LMNAL3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL22390592 0.96 LMNA (0.43) LMNAL3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL10290344 0.90 CHRM2 (0.47) LMNAL3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL23899583 0.90 OPRM1 (0.42) LMNAL3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL12715776 0.89 L3MBTL1 (0.39) LMNAL3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL14086800 0.86 SLC6A4 (0.42) LMNAL3MBTL1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100178333-A1 SUSTAINED RELEASE DOSAGE FORM OF PHENOTHIAZINE DERIVATIVES CONTAINING CHANNELIZER ASTRON RESEARCH LIMITED (IN) 2010-07-15 US disclosed
EP-1976487-A2 SUSTAINED RELEASE DOSAGE FORM OF PHENOTHIAZINE DERIVATIVES CONTAINING CHANNELIZER Astron Research Limited (IN) 2008-10-08 EP disclosed
WO-2007086079-A2 SUSTAINED RELEASE DOSAGE FORM OF PHENOTHIAZINE DERIVATIVES CONTAINING CHANNELIZER ASTRON RESEARCH LIMITED (IN) 2007-08-02 WO disclosed
US-4933346-A CARDIOVASCULAR AND CEREBROVASCULAR DISORDERS HOECHST AKTIENGESELLSCHAFT (DE) 1990-06-12 US disclosed
US-4918073-A CALCIUM ANTAGONISTS HOECHST AKTIENGESELLSCHAFT (DE) 1990-04-17 US disclosed