Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22390592 | 0.94 | LMNA (0.43) | OPRM1CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL23957178 | 0.92 | LMNA (0.45) | OPRM1CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL28887787 | 0.92 | LMNA (0.45) | OPRM1CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL24404816 | 0.92 | LMNA (0.45) | OPRM1CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL22236667 | 0.90 | LMNA (0.43) | OPRM1CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL22236670 | 0.90 | LMNA (0.43) | OPRM1CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL3229094 | 0.90 | LMNA (0.43) | OPRM1CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL14086800 | 0.88 | SLC6A4 (0.42) | OPRM1CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL10290344 | 0.84 | CHRM2 (0.47) | OPRM1CHRM2HTR1AADRA2AADORA3 | |
| SCHEMBL15417855 | 0.83 | SLC6A4 (0.54) | OPRM1CHRM2HTR1AADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210308123-A1 | NLRP3 MODULATORS | INNATE TUMOR IMMUNITY INC (US) | 2021-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210308123-A1 | NLRP3 MODULATORS | NLRP3, NLRP1, PYCARD | OPRM1 3660/4885CHRM2 4375/4885HTR1A 1428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.