SCHEMBL3229799

SCHEMBL3229799

C=C(C(N)=O)C(C)(C)CC

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
RIPK1 Q13546 1/20 0.32
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL3915936 0.98 TDP1 (0.38) TDP1RIPK1
SCHEMBL10701254 0.83 LMNA (0.42) TDP1LMNAHSD17B10
SCHEMBL1135166 0.80 TDP1 (0.39) TDP1
SCHEMBL28124390 0.80 TDP1 (0.39) TDP1
SCHEMBL21016285 0.80 TDP1 (0.39) TDP1LMNAHSD17B10
SCHEMBL159079 0.78 TDP1 (0.38) TDP1
SCHEMBL27643078 0.78 TDP1 (0.38) TDP1
SCHEMBL1963590 0.77 TET2 (0.38) RIPK1
SCHEMBL2138939 0.77 TET2 (0.38) RIPK1
SCHEMBL9126102 0.76 KDM4E (0.46) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11492432-B2 Resin for nanoimprinting, laminate containing resin for nanoimprinting, printed board containing resin for nanoimprinting, and method for producing nanoimprint substrate JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2022-11-08 US disclosed
CN-114269822-A Elastomer composition for actuator, actuator component and actuator element 引能仕株式会社 2022-04-01 CN disclosed
CN-114258416-A Elastomer composition for actuator, actuator component and actuator element 引能仕株式会社 2022-03-29 CN disclosed
WO-2021038993-A1 ELASTOMER COMPOSITION FOR ACTUATOR, ACTUATOR MEMBER, AND ACTUATOR ELEMENT JXTGエネルギー株式会社 2021-03-04 WO disclosed
WO-2021039821-A1 ELASTOMER COMPOSITION FOR ACTUATOR, ACTUATOR MEMBER, AND ACTUATOR ELEMENT ENEOS株式会社 2021-03-04 WO disclosed
US-20200223125-A1 RESIN FOR NANOIMPRINTING, LAMINATE CONTAINING RESIN FOR NANOIMPRINTING, PRINTED BOARD CONTAINING RESIN FOR NANOIMPRINTING, AND METHOD FOR PRODUCING NANOIMPRINT SUBSTRATE JAPAN SCIENCE & TECH AGENCY (JP) 2020-07-16 US disclosed
CN-110776438-A (Z, E) -configuration pentadiene amide compound and synthesis method thereof 杭州师范大学 2020-02-11 CN disclosed
US-20150298387-A1 RESIN FOR NANOIMPRINTING, LAMINATE CONTAINING RESIN FOR NANOIMPRINTING, PRINTED BOARD CONTAINING RESIN FOR NANOIMPRINTING, AND METHOD FOR PRODUCING NANOIMPRINT SUBSTRATE JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2015-10-22 US disclosed
US-8303943-B2 Ampholytic copolymer based on quaternized nitrogen-containing monomers BASF SE (DE) 2012-11-06 US disclosed
US-20100068156-A1 AMPHOLYTIC COPOLYMER BASED ON QUATERNIZED NITROGEN-CONTAINING MONOMERS BASF SE (DE) 2010-03-18 US disclosed
EP-2064253-B1 AMPHOLYTIC COPOLYMER BASED ON QUATERNIZED NITROGEN-CONTAINING MONOMERS BASF SE (DE) 2009-11-18 EP disclosed
WO-2009116454-A1 WATER-BASED PAINT COMPOSITIONS AND MULTILAYER COATING FILM-FORMING METHODS KANSAI PAINT CO., LTD. (JP) 2009-09-24 WO disclosed
WO-2009075392-A1 COATING COMPOSITION AND METHOD FOR FORMING MULTILAYER COATING FILM KANSAI PAINT CO., LTD. (JP) 2009-06-18 WO disclosed
US-7442724-B2 Dispersants for preparing aqueous pigment pastes GOLDSCHMIDT GMBH (DE) 2008-10-28 US disclosed
EP-1786792-A2 THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY Astellas Pharma Inc. (JP) 2007-05-23 EP disclosed
WO-2007013684-A2 AQUEOUS CLEAR COATING COMPOSITION AND METHOD FOR FORMING MULTILAYER TOPCOAT FILM KANSAI PAINT CO., LTD. (JP) 2007-02-01 WO disclosed
WO-2006011631-A2 THIAZOLE DERIVATIVES HAVING VAP-1 INHIBITORY ACTIVITY ASTELLAS PHARMA INC. (JP) 2006-02-02 WO disclosed
US-20050085563-A1 Dispersants for preparing aqueous pigment pastes EVONIK GOLDSCHMIDT GMBH (DE) 2005-04-21 US disclosed
EP-0783030-A1 Aqueous emulsion adhesive SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100068156-A1 AMPHOLYTIC COPOLYMER BASED ON QUATERNIZED NITROGEN-CONTAINING MONOMERS NGLY1, NAAA, NIT2 TDP1 1288/4885RIPK1 4718/4885LMNA 3739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.