Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | HPD | P32754 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL323013 | 0.95 | KDM4E (0.37) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL321649 | 0.93 | KDM4E (0.48) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL17074452 | 0.83 | KDM4E (0.39) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL17074451 | 0.82 | KDM4E (0.39) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL327753 | 0.80 | KDM4E (0.41) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL321841 | 0.79 | MAPT (0.42) | KDM4EHSD17B10ALDH1A1GAAPOLB | |
| SCHEMBL323368 | 0.70 | NPC1 (0.43) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL322028 | 0.68 | MAPK8 (0.34) | KDM4EHSD17B10ALDH1A1GAAHPGD | |
| SCHEMBL14927289 | 0.68 | ADORA3 (0.43) | KDM4EHSD17B10ALDH1A1HPGDADORA2B | |
| SCHEMBL1931446 | 0.68 | HTT (0.42) | ALDH1A1MAPK1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590976-A1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004732-A1 | IMIDAZOPYRIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |