Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | NQO2 | P16083 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898025 | 0.88 | MTNR1A (0.68) | MTNR1AHPGDTRPV1ALDH1A1NQO2 | |
| SCHEMBL3237378 | 0.85 | MTNR1A (0.56) | SMN1; SMN2MTNR1ATRPV1NQO2NPC1 | |
| SCHEMBL3486077 | 0.84 | MTNR1A (0.62) | SMN1; SMN2MTNR1AHPGDTRPV1NQO2 | |
| SCHEMBL3240519 | 0.84 | MTNR1A (0.56) | SMN1; SMN2MTNR1ATRPV1NQO2NPC1 | |
| SCHEMBL3235212 | 0.82 | MTNR1A (0.54) | MTNR1ANQO2MTNR1B | |
| SCHEMBL3226619 | 0.81 | MAPT (0.51) | SMN1; SMN2MTNR1AHPGDALDH1A1NPC1 | |
| SCHEMBL1567114 | 0.81 | MTNR1A (0.73) | MTNR1ATRPV1NQO2MTNR1B | |
| SCHEMBL11261052 | 0.80 | NPC1 (0.61) | SMN1; SMN2HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL5437839 | 0.80 | MTNR1A (0.68) | MTNR1ATRPV1CYP3A4CYP2C19NQO2 | |
| SCHEMBL29941181 | 0.79 | MTNR1A (0.73) | MTNR1ANQO2MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022355-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | PURDUE RESEARCH FOUNDATION (US) | 2010-02-25 | — | — | WO | disclosed |