Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.47 |
| ▸ | NQO2 | P16083 | 4/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27382856 | 0.87 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2TRPV1 | |
| SCHEMBL27382865 | 0.86 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2TRPV1NPC1 | |
| SCHEMBL3232172 | 0.85 | SMN1; SMN2 (0.62) | MTNR1AMTNR1BNQO2TRPV1SMN1; SMN2 | |
| SCHEMBL3240519 | 0.85 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2TRPV1SMN1; SMN2 | |
| SCHEMBL3235212 | 0.83 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL3226619 | 0.82 | MAPT (0.51) | MTNR1ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL29494284 | 0.81 | NPC1 (0.69) | NPC1RAB9AATM | |
| SCHEMBL4092749 | 0.80 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2TRPV1NPC1 | |
| SCHEMBL3235168 | 0.80 | TRPV1 (0.66) | MTNR1AMTNR1BNQO2TRPV1NPC1 | |
| SCHEMBL7898025 | 0.79 | MTNR1A (0.68) | MTNR1AMTNR1BNQO2TRPV1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024086132-A1 | PROTACS TARGETING VIRAL ENZYMES FOR PRECISE TREATMENT OF COVID-19 | OHIO UNIVERSITY (US) | 2024-04-25 | — | — | WO | disclosed |
| WO-2021189046-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF SARS-COV-2 | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2021-09-23 | — | — | WO | disclosed |
| WO-2010022355-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | PURDUE RESEARCH FOUNDATION (US) | 2010-02-25 | — | — | WO | disclosed |