Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019158 | 0.84 | AKR1C3 (0.47) | MAPTALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL3237378 | 0.82 | MTNR1A (0.56) | MTNR1ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL3232172 | 0.81 | SMN1; SMN2 (0.62) | MTNR1AALDH1A1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL3240519 | 0.81 | MTNR1A (0.56) | MTNR1ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL3239528 | 0.81 | LMNA (0.47) | MAPTHTTMEN1KMT2ALMNA | |
| SCHEMBL7897974 | 0.81 | MEN1 (0.67) | MAPTMTNR1AALDH1A1HTTMEN1 | |
| SCHEMBL3235212 | 0.79 | MTNR1A (0.54) | MTNR1AMEN1KMT2A | |
| SCHEMBL3239535 | 0.79 | RORC (0.46) | MAPTMEN1KMT2ALMNARORC | |
| SCHEMBL13844161 | 0.77 | ALDH1A1 (0.54) | MAPTALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL30344965 | 0.77 | KMT2A (0.48) | MAPTMTNR1AALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022355-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | PURDUE RESEARCH FOUNDATION (US) | 2010-02-25 | — | — | WO | disclosed |