Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.56 |
| ▸ | NQO2 | P16083 | 6/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235212 | 0.89 | MTNR1A (0.54) | MTNR1ANQO2MTNR1B | |
| SCHEMBL3237378 | 0.85 | MTNR1A (0.56) | MTNR1ANQO2MTNR1BTRPV1SMN1; SMN2 | |
| SCHEMBL3232172 | 0.84 | SMN1; SMN2 (0.62) | MTNR1ANQO2MTNR1BTRPV1SMN1; SMN2 | |
| SCHEMBL3226619 | 0.81 | MAPT (0.51) | MTNR1ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7898025 | 0.78 | MTNR1A (0.68) | MTNR1ANQO2MTNR1BTRPV1NPC1 | |
| SCHEMBL27724020 | 0.75 | MTNR1A (0.73) | MTNR1ANQO2MTNR1B | |
| SCHEMBL3486077 | 0.75 | MTNR1A (0.62) | MTNR1ANQO2MTNR1BTRPV1SMN1; SMN2 | |
| SCHEMBL1567114 | 0.74 | MTNR1A (0.73) | MTNR1ANQO2MTNR1BTRPV1CA12 | |
| SCHEMBL2608948 | 0.73 | MTNR1A (0.68) | MTNR1ANQO2MTNR1BTRPV1 | |
| SCHEMBL5437839 | 0.73 | MTNR1A (0.68) | MTNR1ANQO2MTNR1BTRPV1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022355-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | PURDUE RESEARCH FOUNDATION (US) | 2010-02-25 | — | — | WO | disclosed |