Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1350777 | 1.00 | DPP4 (0.38) | DPP4F2HTR2AHRH1OPRM1 | |
| SCHEMBL3237718 | 0.96 | DPP4 (0.38) | DPP4F2HTR2AHRH1OPRM1 | |
| SCHEMBL3245048 | 0.94 | SLC6A2 (0.40) | DPP4F2 | |
| SCHEMBL3232917 | 0.86 | SLC6A2 (0.34) | DPP4F2HTR2AHRH1AOC3 | |
| SCHEMBL3243802 | 0.86 | OPRL1 (0.35) | DPP4F2OPRL1AOC3LMNA | |
| SCHEMBL3237835 | 0.79 | CHRM2 (0.36) | DPP4F2AOC3 | |
| SCHEMBL3915316 | 0.79 | OPRM1 (0.45) | HTR2AOPRM1OPRK1OPRL1AOC3 | |
| SCHEMBL3042414 | 0.78 | SLC6A3 (0.40) | AOC3 | |
| SCHEMBL3244382 | 0.78 | DPP4 (0.32) | DPP4F2HTR2AHRH1OPRM1 | |
| SCHEMBL3236836 | 0.75 | LMNA (0.40) | HTR2AHRH1OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020548-A1 | GLYT1 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-02-25 | — | — | WO | disclosed |