Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.52 |
| ▸ | IGF1R | P08069 | 2/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13356415 | 0.86 | GRM4 (0.47) | GPR55CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3246352 | 0.84 | CTSC (0.53) | CTSCIGF1RSYKMAPTGALR2 | |
| SCHEMBL3247964 | 0.82 | CTSC (0.49) | CTSCIGF1RSYKKDRABL1 | |
| SCHEMBL3245277 | 0.80 | ABL1 (0.55) | CTSCABL1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3245571 | 0.80 | ABL1 (0.59) | CTSCSYKDYRK1AABL1MAPT | |
| SCHEMBL3247802 | 0.80 | BRAF (0.58) | CTSCSYKKDRDYRK1AABL1 | |
| SCHEMBL1704 | 0.79 | ABL1 (0.65) | IGF1RSYKABL1KIT | |
| SCHEMBL30562384 | 0.79 | NPY5R (0.67) | NPY5RKDRDYRK1AKCNH2ABL1 | |
| SCHEMBL13362351 | 0.79 | NPY5R (0.67) | NPY5RKDRDYRK1AKCNH2ABL1 | |
| SCHEMBL3242880 | 0.79 | BRAF (0.54) | CTSCSYKKDRABL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | claimed |
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |