Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 9/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GALR2 | O43603 | 1/20 | 0.44 |
| ▸ | GALR1 | P47211 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243096 | 0.84 | CTSC (0.61) | CTSCKDM4EGAAMAPTMEN1 | |
| SCHEMBL3234950 | 0.84 | CTSC (0.52) | CTSCSYKIGF1RGALR2GALR1 | |
| SCHEMBL3242880 | 0.82 | BRAF (0.54) | CTSCSYKMAPTKMT2A | |
| SCHEMBL3247964 | 0.81 | CTSC (0.49) | CTSCSYKIGF1RGALR2GALR1 | |
| SCHEMBL3244704 | 0.80 | SYK (0.52) | CTSCSYKIGF1RGAAGALR2 | |
| SCHEMBL3247690 | 0.79 | IGF1R (0.53) | CTSCSYKIGF1RGALR2GALR1 | |
| SCHEMBL3245571 | 0.79 | ABL1 (0.59) | CTSCSYKKDM4EMAPT | |
| SCHEMBL3247802 | 0.79 | BRAF (0.58) | CTSCSYKKDM4EMAPTMEN1 | |
| SCHEMBL3245277 | 0.79 | ABL1 (0.55) | CTSCMAPTMEN1KMT2AKIF11 | |
| SCHEMBL3239225 | 0.79 | KIF11 (0.53) | CTSCSYKIGF1RGALR2GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | claimed |
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |