Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262036 | 0.90 | ADRB3 (0.43) | LDHA | |
| SCHEMBL1219106 | 0.79 | SLC6A4 (0.59) | LDHASLC6A4ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL11218889 | 0.78 | ALOX15 (0.46) | LDHAHTTKDM4EMITFALDH1A1 | |
| SCHEMBL13003651 | 0.78 | ALOX15 (0.46) | LDHAHTTKDM4EMITFALDH1A1 | |
| SCHEMBL3264693 | 0.78 | PPARD (0.51) | TAS2R14HTTPPARDPPARANPC1 | |
| SCHEMBL8244070 | 0.76 | ALOX15 (0.50) | LDHAHTTKDM4EMITFALDH1A1 | |
| SCHEMBL2759522 | 0.73 | HTT (0.51) | L3MBTL1HTTKDM4EMITFALDH1A1 | |
| SCHEMBL3235280 | 0.73 | TAAR1 (0.47) | SLC6A4HTTKDM4EALDH1A1NPC1 | |
| SCHEMBL10839564 | 0.73 | SLC6A4 (0.53) | SLC6A4 | |
| SCHEMBL20061670 | 0.73 | ALOX15 (0.60) | LDHAHTTKDM4EMITFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030787-A1 | ESTROGEN RECEPTOR LIGANDS | RADIUS HEALTH, INC. (US) | 2010-03-18 | — | — | WO | disclosed |