Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 10/20 | 0.51 |
| ▸ | PPARA | Q07869 | 10/20 | 0.51 |
| ▸ | PPARG | P37231 | 8/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1346881 | 0.79 | LMNA (0.76) | TAS2R14LMNAHTTNPC1MAPK1 | |
| SCHEMBL3235287 | 0.78 | LDHA (0.44) | PPARDPPARATAS2R14LMNAHTT | |
| SCHEMBL7639644 | 0.77 | HTT (0.58) | PPARGLMNAHTT | |
| SCHEMBL1347457 | 0.77 | HTT (0.68) | TAS2R14LMNAHTTNPC1MAPK1 | |
| SCHEMBL1346076 | 0.74 | TAS2R14 (0.46) | TAS2R14LMNAHTTNPC1EPHX2 | |
| SCHEMBL3262036 | 0.72 | ADRB3 (0.43) | — | |
| SCHEMBL3940426 | 0.72 | HTT (0.61) | LMNAHTTNPC1MAPK1RAB9A | |
| SCHEMBL6441737 | 0.71 | ALDH1A1 (0.73) | LMNAHTTNPC1MAPK1RAB9A | |
| SCHEMBL13003651 | 0.71 | ALOX15 (0.46) | HTT | |
| SCHEMBL11218889 | 0.71 | ALOX15 (0.46) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030787-A1 | ESTROGEN RECEPTOR LIGANDS | RADIUS HEALTH, INC. (US) | 2010-03-18 | — | — | WO | disclosed |