Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | FOS | P01100 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235287 | 0.90 | LDHA (0.44) | LDHA | |
| SCHEMBL3242309 | 0.84 | ESR1 (0.46) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL3264693 | 0.72 | PPARD (0.51) | — | |
| SCHEMBL1219106 | 0.71 | SLC6A4 (0.59) | ALOX15ALOX12LDHA | |
| SCHEMBL27682804 | 0.71 | ESR1 (0.61) | ALOX15ESR1ESR2 | |
| SCHEMBL11218889 | 0.70 | ALOX15 (0.46) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL13003651 | 0.70 | ALOX15 (0.46) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL21402271 | 0.70 | FOS (0.62) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL8244070 | 0.68 | ALOX15 (0.50) | ALOX15ALOX12FOSTTRJUN | |
| SCHEMBL345525 | 0.68 | LDHA (0.53) | CALM1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010030787-A1 | ESTROGEN RECEPTOR LIGANDS | RADIUS HEALTH, INC. (US) | 2010-03-18 | — | — | WO | disclosed |