Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262760 | 0.85 | ALOX15 (0.66) | ESRRGALDH1A1MAPTNPC1HTT | |
| SCHEMBL7564626 | 0.84 | MAPT (0.50) | ALDH1A1MAPTNPC1HTTMEN1 | |
| SCHEMBL23832296 | 0.84 | HPGD (0.58) | ESRRGALDH1A1NPC1HPGDMEN1 | |
| SCHEMBL129968 | 0.82 | NPC1 (0.82) | ESRRGALDH1A1MAPTNPC1HTT | |
| SCHEMBL3235573 | 0.81 | PKM (0.58) | MAPTNPC1HPGDMEN1KMT2A | |
| SCHEMBL5969148 | 0.81 | ESRRG (0.60) | ESRRGNPC1MEN1KMT2ARAB9A | |
| SCHEMBL27817813 | 0.79 | ESRRG (0.68) | ESRRGALDH1A1MAPTNPC1HTT | |
| SCHEMBL15329262 | 0.79 | ESRRG (0.60) | ESRRGHPGDTSHRALOX5 | |
| SCHEMBL2732841 | 0.79 | CYP1A2 (0.58) | ALDH1A1MAPTHTTKDM4EPOLB | |
| SCHEMBL5707054 | 0.78 | HTT (0.69) | ESRRGALDH1A1MAPTNPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022355-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | PURDUE RESEARCH FOUNDATION (US) | 2010-02-25 | — | — | WO | disclosed |