Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4677052 | 0.78 | HDAC8 (0.39) | RXRARXRBACHEHDAC8HDAC4 | |
| SCHEMBL6771920 | 0.75 | HDAC4 (0.35) | RXRARXRBACHEHDAC8HDAC4 | |
| SCHEMBL23972306 | 0.74 | LMNA (0.53) | RXRARXRBACHEHDAC8HDAC4 | |
| SCHEMBL7357616 | 0.74 | PTGS1 (0.56) | RXRARXRBACHEHDAC8HDAC4 | |
| SCHEMBL1788079 | 0.74 | IDO1 (0.45) | RXRARXRBACHEHDAC8HDAC4 | |
| SCHEMBL16019037 | 0.73 | ACHE (0.46) | RXRARXRBACHEHDAC8HDAC4 | |
| SCHEMBL28988616 | 0.73 | ACHE (0.46) | RXRARXRBACHEHDAC8HDAC4 | |
| SCHEMBL1787675 | 0.72 | ACHE (0.45) | RXRARXRBACHEHDAC8HDAC4 | |
| SCHEMBL5871219 | 0.72 | PNMT (0.42) | RXRARXRBACHEHDAC8HDAC4 | |
| SCHEMBL1787680 | 0.71 | ACHE (0.44) | RXRARXRBACHEHDAC8HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024422-A1 | AMIDE COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-04 | — | — | WO | disclosed |
| WO-2010024365-A1 | AMIDE COMPOUNDS AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-04 | — | — | WO | disclosed |