Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3884603 | 0.78 | PGK1 (0.42) | ACP3ALDH1A1PTPN1TSHRPGK1 | |
| SCHEMBL779166 | 0.76 | PTPN1 (0.41) | KCNN4ALDH1A1NPC1RAB9APTPN1 | |
| SCHEMBL3234321 | 0.73 | FDPS (0.40) | KCNN4SMN1; SMN2ACP3ALDH1A1HTR2A | |
| SCHEMBL18242369 | 0.72 | KCNN4 (0.45) | KCNN4SMN1; SMN2ALDH1A1NPC1GLA | |
| SCHEMBL4298643 | 0.72 | KCNN4 (0.45) | KCNN4ALDH1A1HTR2AHTR2CADRA1A | |
| SCHEMBL30530487 | 0.72 | KCNN4 (0.45) | KCNN4ALDH1A1HTR2AHTR2CADRA1A | |
| SCHEMBL8895713 | 0.72 | KCNN4 (0.45) | KCNN4ALDH1A1HTR2AHTR2CADRA1A | |
| SCHEMBL8167395 | 0.71 | CES2 (0.41) | KCNN4ALDH1A1NPC1GLARAB9A | |
| SCHEMBL7571745 | 0.71 | KCNN4 (0.48) | KCNN4SMN1; SMN2ALDH1A1GLARAB9A | |
| SCHEMBL78489 | 0.71 | TSHR (0.50) | KCNN4SMN1; SMN2ALDH1A1NPC1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140073608-A1 | Butyrylcholinesterase Inhibitors | MGP BIOTECHNOLOGIES, LLC (US) | 2014-03-13 | — | — | US | disclosed |
| US-20100069337-A1 | BUTYRYLCHOLINESTERASE INHIBITORS | JAL THERAPEUTICS, LLC | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073608-A1 | Butyrylcholinesterase Inhibitors | BCHE, ACHE, PSEN1 | KCNN4 3310/4885SMN1; SMN2 178/4885ACP3 261/4885 |
| US-20100069337-A1 | BUTYRYLCHOLINESTERASE INHIBITORS | BCHE, ACHE, PSEN1 | KCNN4 3310/4885SMN1; SMN2 178/4885ACP3 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.