Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832296 | 0.92 | HPGD (0.58) | HPGDSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL3233643 | 0.78 | TAAR1 (0.51) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL9492896 | 0.78 | HPGD (0.77) | HPGDSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL3235358 | 0.77 | ESRRG (0.61) | HPGDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL7564626 | 0.76 | MAPT (0.50) | NPC1RAB9AKMT2AMEN1POLB | |
| SCHEMBL3235573 | 0.75 | PKM (0.58) | HPGDSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL13162414 | 0.75 | HPGD (0.69) | HPGDSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL486382 | 0.75 | TSHR (0.80) | HPGDSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL21443284 | 0.74 | HPGD (0.68) | HPGDSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL13164043 | 0.74 | HPGD (0.68) | HPGDSMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022355-A1 | COMPOUNDS AND METHODS FOR TREATING RESPIRATORY DISEASES | PURDUE RESEARCH FOUNDATION (US) | 2010-02-25 | — | — | WO | disclosed |