SCHEMBL3236362

SCHEMBL3236362

NC(=O)c1ccccc1-c1cc(F)cc(F)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.63
GRM5 P41594 1/20 0.52
CTSA P10619 2/20 0.51
ALOX5AP P20292 1/20 0.49
FEN1 P39748 1/20 0.49
CHEK1 O14757 1/20 0.47
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
MAPT P10636 2/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
HSD17B10 Q99714 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
SLC9A1 P19634 1/20 0.43
CSNK1A1 P48729 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27926363 0.86 BCAT2 (0.76) BCAT2GRM5ALOX5APFEN1CHEK1
SCHEMBL30100449 0.86 BCAT2 (0.51) BCAT2GRM5CTSAALOX5APFEN1
SCHEMBL3632646 0.86 BCAT2 (0.65) BCAT2GRM5ALOX5APFEN1CHEK1
SCHEMBL29818012 0.86 BCAT2 (0.65) BCAT2GRM5ALOX5APFEN1CHEK1
SCHEMBL1555170 0.84 BCAT2 (0.61) BCAT2GRM5CTSAALOX5APFEN1
SCHEMBL29435113 0.84 BCAT2 (0.61) BCAT2GRM5CTSAALOX5APFEN1
SCHEMBL17796931 0.83 ALDH1A1 (0.48) BCAT2NPC1RAB9AMAPTALDH1A1
SCHEMBL2567641 0.83 BCAT2 (0.71) BCAT2ALOX5APFEN1CHEK1NPC1
SCHEMBL30338453 0.82 BCAT2 (0.54) BCAT2GRM5CTSAALOX5APFEN1
Hydrochloric Acid SCHEMBL5797256 0.81 BCAT2 (0.69) BCAT2ALOX5APFEN1CHEK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090011935-A1 Method of Inducing Tolerance of Plants Against Bacterioses BASF SE (DE) 2009-01-08 US claimed
EP-1996018-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2008-12-03 EP claimed
WO-2007104658-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2007-09-20 WO claimed
EP-2285779-B1 Method for manufacturing aryl carboxamides BASF SE (DE) 2013-03-27 EP disclosed
EP-2392662-A2 Plant produtivity enhancement by combining chemical agents with transgenic modifications BASF SE (DE) 2011-12-07 EP disclosed
EP-2259675-A2 FUNGICIDAL COMPOSITIONS COMPRISING 3'-BROMINE-2,3,4,6'-TETRAMETHOXY-2'-6-DIMETHYLBENZOPHENONE BASF SE (DE) 2010-12-15 EP disclosed
US-20100093715-A1 Plant productivity enhancement by combining chemical agents with transgenic modifications BASF SE (DE) 2010-04-15 US disclosed
WO-2010015634-A1 METHOD FOR SCREENING FOR A PLANT PROTECTANT BASF SE (DE) 2010-02-11 WO disclosed
EP-2150106-A2 ACTIVE INGREDIENT COMPOSITIONS FOR PLANT PROTECTION BASF SE (DE) 2010-02-10 EP disclosed
WO-2010010005-A2 OIL-IN-WATER EMULSION COMPRISING SOLVENT, WATER, SURFACTANT AND PESTICIDE BASF SE (DE) 2010-01-28 WO disclosed
EP-2142293-A2 ENZYMATIC METHOD FOR THE PRODUCTION OF MICROCAPSULES BASF SE (DE) 2010-01-13 EP disclosed
WO-2009135860-A1 METHOD FOR MANUFACTURING ARYL CARBOXAMIDES BASF SE (DE) 2009-11-12 WO disclosed
WO-2009135865-A1 PROCESS FOR THE PRODUCTION OF PARTICLES COMPRISING ACTIVE AGROCHEMICAL INGREDIENTS IN AMORPHOUS FORM BASF SE (DE) 2009-11-12 WO disclosed
WO-2009124920-A2 EMULSIFIABLE CONCENTRATE BASF SE (DE) 2009-10-15 WO disclosed
WO-2009103813-A2 FUNGICIDAL COMPOSITIONS COMPRISING 3'-BROMINE-2,3,4,6'-TETRAMETHOXY-2'-6-DIMETHYLBENZOPHENONE BASF SE (DE) 2009-08-27 WO disclosed
US-20090011935-A1 Method of Inducing Tolerance of Plants Against Bacterioses BASF SE (DE) 2009-01-08 US disclosed
EP-1996018-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2008-12-03 EP disclosed
WO-2008132179-A2 ACTIVE INGREDIENT COMPOSITIONS FOR PLANT PROTECTION BASF SE (DE) 2008-11-06 WO disclosed
WO-2008132067-A2 ENZYMATIC METHOD FOR THE PRODUCTION OF MICROCAPSULES BASF SE (DE) 2008-11-06 WO disclosed
WO-2007104658-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2007-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090011935-A1 Method of Inducing Tolerance of Plants Against Bacterioses BROX, CAT, SLC11A2 BCAT2 142/4885GRM5 3400/4885CTSA 1543/4885
US-20100093715-A1 Plant productivity enhancement by combining chemical agents with transgenic modifications CBR3, MYB, HACL2 BCAT2 716/4885GRM5 1878/4885CTSA 4206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.