Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.55 |
| ▸ | FBP1 | P09467 | 1/20 | 0.52 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235250 | 0.81 | SLC40A1 (0.50) | SLC40A1FBP1PTGES2KITHDAC3 | |
| SCHEMBL16235316 | 0.81 | SLC40A1 (0.52) | SLC40A1FBP1PTGES2KITHDAC3 | |
| SCHEMBL3244704 | 0.76 | SYK (0.52) | MEN1KMT2AALDH1A1 | |
| SCHEMBL29023883 | 0.76 | MEN1 (0.69) | MEN1KMT2AALDH1A1HDAC3HDAC4 | |
| SCHEMBL3241930 | 0.76 | FYN (0.51) | SLC40A1FBP1PTGES2KITHDAC3 | |
| SCHEMBL22441824 | 0.75 | PGR (0.59) | MEN1KMT2ASLC40A1PTGES2ALDH1A1 | |
| SCHEMBL3249395 | 0.74 | NPC1 (0.70) | MEN1KMT2AALDH1A1KDM4EPKM | |
| SCHEMBL13485914 | 0.74 | SLC40A1 (0.60) | SLC40A1FBP1PTGES2KITHDAC3 | |
| SCHEMBL18525587 | 0.73 | KDM5A (0.49) | MEN1KMT2AALDH1A1KDM4EPKM | |
| SCHEMBL1267178 | 0.73 | ALDH1A1 (0.59) | MEN1KMT2ASLC40A1PTGES2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |