Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 2/20 | 0.50 |
| ▸ | CTSC | P53634 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GALR2 | O43603 | 2/20 | 0.47 |
| ▸ | GALR1 | P47211 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22404991 | 0.83 | SYK (0.64) | SYKIGF1RCTSCEPHX2MAPT | |
| SCHEMBL20267695 | 0.83 | KCNH2 (0.49) | CTSCNPC1RAB9AABL1BCR | |
| SCHEMBL3247623 | 0.81 | SYK (0.49) | SYKIGF1RCTSCGALR2GALR1 | |
| SCHEMBL3246352 | 0.80 | CTSC (0.53) | SYKIGF1RCTSCGALR2GALR1 | |
| SCHEMBL3234950 | 0.79 | CTSC (0.52) | SYKIGF1RCTSCGALR2GALR1 | |
| SCHEMBL18525587 | 0.78 | KDM5A (0.49) | NPC1RAB9AMAPTALDH1A1GAA | |
| SCHEMBL21088768 | 0.77 | SYK (0.46) | SYKIGF1RCTSCGALR2GALR1 | |
| SCHEMBL3238245 | 0.76 | MEN1 (0.59) | ALDH1A1MEN1KMT2A | |
| SCHEMBL3249395 | 0.76 | NPC1 (0.70) | NPC1RAB9AALDH1A1HPGDTSHR | |
| SCHEMBL3247690 | 0.76 | IGF1R (0.53) | SYKIGF1RCTSCGALR2GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |