Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 10/20 | 0.50 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.50 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 3/20 | 0.42 |
| ▸ | NOS3 | P29474 | 3/20 | 0.42 |
| ▸ | NOS1 | P29475 | 3/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methionine SCHEMBL3883236 | 1.00 | BHMT (0.50) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL27559551 | 1.00 | BHMT (0.50) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL2260603 | 0.94 | BHMT (0.50) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL27691481 | 0.94 | BHMT (0.50) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Methionine SCHEMBL2260610 | 0.94 | BHMT (0.50) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Methionine SCHEMBL14485913 | 0.93 | BHMT (0.56) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Methionine SCHEMBL1163783 | 0.93 | BHMT (0.56) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL27265226 | 0.93 | BHMT (0.56) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL1163782 | 0.93 | BHMT (0.56) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL2804076 | 0.93 | BHMT (0.56) | BHMTBHMT2RNPEPNOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117441021-A | Methods and compositions for altering protein accumulation | 孟山都技术有限公司 | 2024-01-23 | — | — | CN | claimed |
| US-20040077031-A1 | Novel methionine aminopeptidase-2 and uses thereof | ABBOTT LABORATORIES | 2004-04-22 | — | — | US | claimed |
| EP-0757719-A4 | -g(a)-1-ANTICHYMOTRYPSIN ANALOGUES HAVING CHYMASE INHIBITING ACTIVITY | UNIV PENNSYLVANIA (US) | 1999-09-29 | — | — | EP | claimed |
| US-5723316-A | α-1-antichymotrypsin analogues having chymase inhibiting activity | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-03-03 | — | — | US | claimed |
| EP-0757719-A1 | $g(a)-1-ANTICHYMOTRYPSIN ANALOGUES HAVING CHYMASE INHIBITING ACTIVITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1997-02-12 | — | — | EP | claimed |
| WO-1995027053-A1 | α-1-ANTICHYMOTRYPSIN ANALOGUES HAVING CHYMASE INHIBITING ACTIVITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-10-12 | — | — | WO | claimed |
| CN-117441021-A | Methods and compositions for altering protein accumulation | 孟山都技术有限公司 | 2024-01-23 | — | — | CN | disclosed |
| US-11173196-B2 | Vectors for expression of prostate-associated antigens | PFIZER INC. (US) | 2021-11-16 | — | — | US | disclosed |
| EP-3524262-A1 | VECTORS FOR EXPRESSION OF PROSTATE-ASSOCIATED ANTIGENS | Pfizer Inc (US) | 2019-08-14 | — | — | EP | disclosed |
| EP-3062815-B1 | VECTORS FOR EXPRESSION OF PROSTATE-ASSOCIATED ANTIGENS | PFIZER (US) | 2019-01-16 | — | — | EP | disclosed |
| US-20180369352-A1 | VECTORS FOR EXPRESSION OF PROSTATE-ASSOCIATED ANTIGENS | PFIZER (US) | 2018-12-27 | — | — | US | disclosed |
| US-10092636-B2 | Vectors for expression of prostate-associated antigens | PFIZER INC. (US) | 2018-10-09 | — | — | US | disclosed |
| CN-103764641-B | The tricyclic compound of fractional saturation and preparation and application thereof | 扎夫根股份有限公司 | 2016-10-26 | — | — | CN | disclosed |
| US-5674708-A | AMINO ACID AT POSITION 358 IS SELECTED FROM THE GROUP CONSISTING OF ISOLEUCINE, VALINE, ALANINE, ASPARTIC ACID, THREONINE AND GLUTAMIC ACID | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1997-10-07 | — | — | US | disclosed |
| EP-0757719-A1 | $g(a)-1-ANTICHYMOTRYPSIN ANALOGUES HAVING CHYMASE INHIBITING ACTIVITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1997-02-12 | — | — | EP | disclosed |
| EP-0757719-A1 | $g(a)-1-ANTICHYMOTRYPSIN ANALOGUES HAVING CHYMASE INHIBITING ACTIVITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1997-02-12 | — | — | EP | disclosed |
| EP-0754228-A1 | $g(a)-1-ANTICHYMOTRYPSIN ANALOGUES HAVING ELASTASE INHIBITORY ACTIVITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1997-01-22 | — | — | EP | disclosed |
| WO-1995027053-A1 | α-1-ANTICHYMOTRYPSIN ANALOGUES HAVING CHYMASE INHIBITING ACTIVITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-10-12 | — | — | WO | disclosed |
| WO-1995027055-A1 | α-1-ANTICHYMOTRYPSIN ANALOGUES HAVING ELASTASE INHIBITORY ACTIVITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-10-12 | — | — | WO | disclosed |
| WO-1995027053-A1 | α-1-ANTICHYMOTRYPSIN ANALOGUES HAVING CHYMASE INHIBITING ACTIVITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1995-10-12 | — | — | WO | disclosed |