Methionine

Methionine

SCHEMBL3883236

CSCC[C@H](N)C(=O)O.C[C@H](N)C(=O)O.N[C@@H](CO)C(=O)O.N[C@@H](CO)C(=O)O

nearest known ligand 0.75

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 10/20 0.50
BHMT2 Q9H2M3 1/20 0.50
RNPEP Q9H4A4 1/20 0.44
NOS2 P35228 3/20 0.42
NOS3 P29474 3/20 0.42
NOS1 P29475 3/20 0.42
SLC7A5 Q01650 1/20 0.39
GRM8 O00222 1/20 0.39
GRM6 O15303 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GSR P00390 1/20 0.39
CYP1A2 P05177 1/20 0.39
GRIK1 P39086 1/20 0.39
GRM5 P41594 1/20 0.39
GRIA1 P42261 1/20 0.39
GRIA2 P42262 1/20 0.39
GRIA3 P42263 1/20 0.39
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Racemethionine SCHEMBL27559551 1.00 BHMT (0.50) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL3239125 1.00 BHMT (0.50) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL2260603 0.94 BHMT (0.50) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL27691481 0.94 BHMT (0.50) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL2260610 0.94 BHMT (0.50) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL14485913 0.93 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL1163783 0.93 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL27265226 0.93 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL1163782 0.93 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL2804076 0.93 BHMT (0.56) BHMTBHMT2RNPEPNOS2NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1002869-B1 A chemically synthesised artificial promotor for high level expression of transgenes and a method for its synthesis COUNCIL SCIENT IND RES (IN) 2009-01-07 EP claimed
EP-1002869-A1 A chemically synthesised artificial promotor for high level expression of transgenes and a method for its synthesis Council of Scientific and Industrial Research (IN) 2000-05-24 EP claimed