Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 10/20 | 0.50 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.50 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.48 |
| ▸ | NOS2 | P35228 | 3/20 | 0.46 |
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM6 | O15303 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Racemethionine SCHEMBL2260603 | 1.00 | BHMT (0.50) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL27691481 | 1.00 | BHMT (0.50) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL27559551 | 0.94 | BHMT (0.50) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Methionine SCHEMBL3883236 | 0.94 | BHMT (0.50) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Methionine SCHEMBL3239125 | 0.94 | BHMT (0.50) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Methionine SCHEMBL2022415 | 0.93 | BHMT (0.46) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL23361954 | 0.92 | BHMT (0.57) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL126688 | 0.92 | — | — | |
| Racemethionine SCHEMBL287590 | 0.92 | BHMT (0.57) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Methionine SCHEMBL5584463 | 0.92 | BHMT (0.57) | BHMTBHMT2RNPEPNOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920092-A | Prodrugs of glutamine analogs | 约翰霍普金斯大学 | 2021-06-08 | — | — | CN | disclosed |
| US-9090882-B2 | Compositions and methods for enhanced amino acid levels in plants conferred by lysine and/or threonine feedback insensitive aspartate kinase proteins | MONSANTO TECHNOLOGY LLC (US) | 2015-07-28 | — | — | US | disclosed |
| EP-2729570-A2 | REAGENT USABLE FOR THE ISOLATION AND/OR PURIFICATION OF NUCLEIC ACIDS | Qiagen GmbH (DE) | 2014-05-14 | — | — | EP | disclosed |
| WO-2013004710-A2 | REAGENT USABLE FOR THE ISOLATION AND/OR PURIFICATION OF NUCLEIC ACIDS | QIAGEN GMBH (DE) | 2013-01-10 | — | — | WO | disclosed |
| WO-2011113066-A1 | METHODS AND SYSTEMS USING INTEGRATED METABOLOMICS AND PHARMACOKINETICS FOR MULTI-COMPONENT DRUG EVALUATION | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (US) | 2011-09-15 | — | — | WO | disclosed |
| US-20110191898-A1 | Compositions and Methods for Enhanced Amino Acid Levels in Plants | MONSANTO TECHNOLOGY LLC (US) | 2011-08-04 | — | — | US | disclosed |
| WO-2010002876-A2 | COMPOSITIONS AND METHODS FOR ENHANCED AMINO ACID LEVELS IN PLANTS | MONSANTO TECHNOLOGY LLC (US) | 2010-01-07 | — | — | WO | disclosed |
| EP-1572991-A4 | COMPOSITIONS AND METHODS FOR HYDROXILATING EPOTHILONES | BRISTOL MYERS SQUIBB CO (US) | 2007-07-25 | — | — | EP | disclosed |
| EP-1465908-A4 | COMPOSITIONS AND METHODS FOR HYDROXYLATING EPOTHILONES | BRISTOL MYERS SQUIBB CO (US) | 2005-11-30 | — | — | EP | disclosed |
| EP-1572991-A2 | COMPOSITIONS AND METHODS FOR HYDROXILATING EPOTHILONES | Bristol-Myers Squibb Company (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004061116-A2 | COMPOSITIONS AND METHODS FOR HYDROXILATING EPOTHILONES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-07-22 | — | — | WO | disclosed |
| EP-0324789-B1 | METHODS OF REGULATING METABOLIC STABILITY OF PROTEINS | MASSACHUSETTS INST TECHNOLOGY (US) | 2003-08-20 | — | — | EP | disclosed |
| WO-2003057830-A2 | COMPOSITIONS AND METHODS FOR HYDROXYLATING EPOTHILONES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-17 | — | — | WO | disclosed |
| US-5847097-A | Methods of generating desired amino-terminal residues in peptides | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0637247-B1 | TREATMENT OF HERPESVIRUS INFECTION | ALLELIX BIOPHARMA (CA) | 1998-08-19 | — | — | EP | disclosed |
| US-5646017-A | CONTROLLING METABOLIC STABILITY, DEGRADATION, PROTEOLYTIC CLEAVAGE OF FUSED PROTEINS TO UNMASK SPECIFIC AMINO-TERMINAL RESIDUE | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1997-07-08 | — | — | US | disclosed |
| US-5496721-A | PROTEINS AND CELLS FOR GENETICS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1996-03-05 | — | — | US | disclosed |
| US-5196321-A | Gene expression; splitting with protease | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1993-03-23 | — | — | US | disclosed |
| US-5132213-A | Peptide fusion for genetic engineering and protein synthesis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1992-07-21 | — | — | US | disclosed |
| EP-0324789-A1 | METHODS OF REGULATING METABOLIC STABILITY OF PROTEINS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-07-26 | — | — | EP | disclosed |