Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | ADK | P55263 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5505707 | 0.76 | NISCH (0.35) | NISCHMTORADKPDE3BPDE3A | |
| SCHEMBL1558112 | 0.75 | NISCH (0.34) | NISCHMTORADKPDE3BPDE3A | |
| SCHEMBL28581729 | 0.75 | NISCH (0.52) | NISCHMTORADKPDE3BPDE3A | |
| SCHEMBL5491437 | 0.75 | — | — | |
| SCHEMBL30216772 | 0.75 | NISCH (0.52) | NISCHMTORADKPDE3BPDE3A | |
| SCHEMBL1673128 | 0.72 | — | — | |
| SCHEMBL81650 | 0.72 | NISCH (0.59) | NISCHMTORADKPDE3BPDE3A | |
| SCHEMBL197279 | 0.71 | NISCH (0.54) | NISCHMTORADKPDE3BPDE3A | |
| SCHEMBL28425230 | 0.70 | NISCH (0.56) | NISCHMTORADKPDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL1536214 | 0.70 | NISCH (0.56) | NISCHMTORADKPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332964-B | Synthesis method of bidentate pyrazolyl nitrogen heterocyclic palladium carbene compound | 西北大学 | 2024-05-24 | — | — | CN | claimed |
| CN-116332964-A | Synthesis method of bidentate pyrazolyl nitrogen heterocyclic palladium carbene compound | 西北大学 | 2023-06-27 | — | — | CN | claimed |
| CN-109535145-B | 1,3,4-oxa (thia) diazolyl imidazole compound and preparation method and application thereof | 贵州大学 | 2022-05-24 | — | — | CN | claimed |
| CN-119462769-A | Preparation method and application of bimodal linear polyethylene chromium carbene catalyst | 西北大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-116332964-B | Synthesis method of bidentate pyrazolyl nitrogen heterocyclic palladium carbene compound | 西北大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-116332964-B | Synthesis method of bidentate pyrazolyl nitrogen heterocyclic palladium carbene compound | 西北大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-117651551-A | Use and method of using Nrf2 activators to enhance natural killer and/or T cell activity and/or survival | 成白血球细胞公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-116332964-A | Synthesis method of bidentate pyrazolyl nitrogen heterocyclic palladium carbene compound | 西北大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-116332964-A | Synthesis method of bidentate pyrazolyl nitrogen heterocyclic palladium carbene compound | 西北大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-115989225-A | Imidazole-pyrazole derivatives as antibacterial agents | 豪夫迈·罗氏有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-115989227-A | Imidazole-pyrazole derivatives having antibacterial properties | 豪夫迈·罗氏有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-1649848-A | Fused pyrimidines derivatives as antagonists of the corticotropin releasing factor (CRF) | GLAXO GROUP LTD (GB) | 2005-08-03 | — | — | CN | disclosed |
| WO-2005002576-A2 | IMIDAZOLE DERIVATIVES AND THEIR USE AS PROTEIN KINASES INHIBITORS | ASTEX THERAPEUTICS LIMITED (GB) | 2005-01-13 | — | — | WO | disclosed |
| US-20040180881-A1 | Oxazolyl-pyrazole derivatives as kinase inhibitors | PFIZER ITALIA S.R.L. (IT) | 2004-09-16 | — | — | US | disclosed |
| US-20040176400-A1 | Fused pyrimidines as antagonists of the corticotropin releasing factor (crf) | GLAXO GROUP LIMITED (GB) | 2004-09-09 | — | — | US | disclosed |
| EP-1383747-A1 | FUSED PYRIMIDINES AS ANTAGONISTS OF THE CORTICOTROPIN RELEASING FACTOR (CRF) | GLAXO GROUP LIMITED (GB) | 2004-01-28 | — | — | EP | disclosed |
| EP-1377589-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | Pharmacia Italia S.p.A. (IT) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002088095-A1 | FUSED PYRIMIDINES AS ANTAGONISTS OF THE CORTICOTROPIN RELEASING FACTOR (CRF) | GLAXO GROUP LIMITED (GB) | 2002-11-07 | — | — | WO | disclosed |
| WO-2002062804-A1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA S.P.A. (IT) | 2002-08-15 | — | — | WO | disclosed |
| EP-0344634-A1 | Bicyclic carboxamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1989-12-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176400-A1 | Fused pyrimidines as antagonists of the corticotropin releasing factor (crf) | CRH, CRHR1, CRHR2 | NISCH 645/4885MTOR 1866/4885ADK 1053/4885 |
| US-20040180881-A1 | Oxazolyl-pyrazole derivatives as kinase inhibitors | MAP3K15, MAP3K20, MAP3K3 | NISCH 3267/4885MTOR 66/4885ADK 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.