Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7953476 | 0.83 | RECQL (0.61) | ALDH1A1KDM4ESMN1; SMN2HTTGAA | |
| SCHEMBL7956794 | 0.82 | HPGD (0.54) | ALDH1A1RAB9AKDM4EHTTMAPK1 | |
| SCHEMBL7955329 | 0.80 | NPC1 (0.52) | ALDH1A1RAB9ASMN1; SMN2L3MBTL1CA2 | |
| SCHEMBL7024674 | 0.78 | KDM4E (0.51) | ALDH1A1RAB9AKDM4ESMN1; SMN2HTT | |
| SCHEMBL2695687 | 0.77 | ALDH1A1 (0.67) | ALDH1A1RAB9AKDM4ESMN1; SMN2HTT | |
| SCHEMBL12707584 | 0.77 | ALDH1A1 (0.67) | ALDH1A1RAB9AKDM4ESMN1; SMN2HTT | |
| SCHEMBL3240744 | 0.75 | ALDH1A1 (0.55) | ALDH1A1RAB9AKDM4ESMN1; SMN2HTT | |
| SCHEMBL6929919 | 0.73 | RECQL (0.62) | ALDH1A1RAB9ASMN1; SMN2HTTGAA | |
| SCHEMBL10157134 | 0.73 | ALDH1A1 (0.61) | ALDH1A1RAB9AKDM4ESMN1; SMN2HTT | |
| SCHEMBL2695729 | 0.73 | ALDH1A1 (0.61) | ALDH1A1RAB9AKDM4ESMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172064-B1 | METALLOPROTEASE INHIBITOR; ANTIARTHRITIC AGENTS, ANTIDIABETIC AGENTS; ANTITUMOR AGENTS | GLAXO WELLCOME INC. | 2001-01-09 | — | — | US | disclosed |