SCHEMBL3241161

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3230874	0.89	OPRM1 (0.76)	OPRM1OPRD1OPRK1SLC6A2SLC6A4
	SCHEMBL5509157	0.88	OPRM1 (0.81)	OPRM1OPRD1OPRK1SLC6A2SLC6A4
	SCHEMBL5510269	0.85	OPRM1 (0.76)	OPRM1OPRD1OPRK1SLC6A2SLC6A4
	SCHEMBL3239924	0.84	OPRM1 (1.00)	OPRM1OPRD1OPRK1SLC6A2SLC6A4
	SCHEMBL3238503	0.84	OPRM1 (1.00)	OPRM1OPRD1OPRK1SLC6A2SLC6A4
	SCHEMBL3243590	0.84	OPRM1 (1.00)	OPRM1OPRD1OPRK1SLC6A2SLC6A4
	SCHEMBL3240361	0.82	OPRM1 (0.74)	OPRM1OPRD1OPRK1SLC6A2SLC6A4
	Desmetramadol SCHEMBL57246	0.78	OPRM1 (1.00)	OPRM1OPRD1OPRK1SLC6A2SLC6A4
	O-Desmethyl Tramadol SCHEMBL2517055	0.78	OPRM1 (1.00)	OPRM1OPRD1OPRK1SLC6A2SLC6A4
	SCHEMBL7921501	0.78	SLC6A4 (0.77)	OPRM1OPRD1OPRK1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.