Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.40 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037302 | 0.89 | GAA (0.55) | GAAMAPTALDH1A1TP53CYP1A2 | |
| SCHEMBL4365304 | 0.89 | GAA (0.55) | GAAMAPTALDH1A1TP53CYP1A2 | |
| SCHEMBL7044783 | 0.89 | GAA (0.55) | GAAMAPTALDH1A1TP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL10910510 | 0.88 | GAA (0.54) | GAAMAPTALDH1A1TP53CYP1A2 | |
| SCHEMBL28634734 | 0.86 | MTNR1A (0.44) | GAAMAPTALDH1A1TP53CYP1A2 | |
| SCHEMBL4999513 | 0.86 | MTNR1A (0.44) | GAAMAPTALDH1A1TP53CYP1A2 | |
| SCHEMBL1321069 | 0.81 | ALOX15 (0.44) | GAAMAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16879090 | 0.79 | DPP4 (0.57) | ACHEMTNR1AMTNR1BDPP4CA1 | |
| SCHEMBL31370360 | 0.79 | ROCK2 (0.55) | ACHEMTNR1AMTNR1BDPP4CA1 | |
| SCHEMBL7785428 | 0.79 | DPP4 (0.57) | ACHEMTNR1AMTNR1BDPP4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066318-B1 | OXINDOLE DERIVATIVES AS ANTICANCER AGENTS | HOFFMANN LA ROCHE (CH) | 2010-05-12 | — | — | EP | claimed |
| EP-0992524-B1 | Process for preparing polyether polyols | BAYER AG (DE) | 2004-02-18 | — | — | EP | disclosed |
| US-6624321-B2 | Metathesis ring-opening polymerization of cyclic ethers in the presence of catalysts such as aluminum bis(trifluoromethane-sulfonate) phenolate | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-23 | — | — | US | disclosed |
| US-20030097026-A1 | Process for the preparation of polyether polyols | DENNINGER UWE (DE) | 2003-05-22 | — | — | US | disclosed |
| US-6492565-B2 | USING ALKYLENE OXIDE IN PRESENCE OF LEWIS ACID CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-10 | — | — | US | disclosed |
| US-20010053866-A1 | Process for the preparation of polyether polyols | BAYER AKTIENGESELLSCHAFT (DE) | 2001-12-20 | — | — | US | disclosed |
| EP-0992524-A2 | Process for preparing polyether polyols | BAYER AG (DE) | 2000-04-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030097026-A1 | Process for the preparation of polyether polyols | PCBP1, FHIT, PUF60 | GAA 3068/4885MAPT 4187/4885ALDH1A1 3594/4885 |
| US-20010053866-A1 | Process for the preparation of polyether polyols | PCBP1, FHIT, PUF60 | GAA 3068/4885MAPT 4187/4885ALDH1A1 3594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.