Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 5/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045313 | 0.89 | METTL3 (0.55) | METTL3CXCR2P2RX7 | |
| SCHEMBL1045314 | 0.89 | METTL3 (0.55) | METTL3CXCR2P2RX7 | |
| SCHEMBL3243314 | 0.89 | METTL3 (0.53) | METTL3EGFRPLA2G4ALMNA | |
| SCHEMBL3239885 | 0.88 | METTL3 (0.48) | METTL3PLA2G4AP2RX7LMNA | |
| SCHEMBL3239627 | 0.87 | METTL3 (0.47) | METTL3EGFRPLA2G4A | |
| SCHEMBL3241137 | 0.85 | METTL3 (0.40) | METTL3P2RX7 | |
| SCHEMBL3240262 | 0.84 | METTL3 (0.54) | METTL3PLA2G4AP2RX7LMNA | |
| SCHEMBL3241799 | 0.84 | METTL3 (0.54) | METTL3PLA2G4AP2RX7LMNA | |
| SCHEMBL3243346 | 0.82 | METTL3 (0.60) | METTL3EGFRPLA2G4ALMNA | |
| SCHEMBL3235872 | 0.82 | METTL3 (0.50) | METTL3EGFRPLA2G4ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |