Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | CFD | P00746 | 2/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243314 | 0.93 | METTL3 (0.53) | METTL3PLA2G4ACFDLMNA | |
| SCHEMBL3237655 | 0.92 | METTL3 (0.54) | METTL3P2RX7CFDHIF1A | |
| SCHEMBL3242298 | 0.91 | METTL3 (0.44) | METTL3P2RX7CFDHIF1ALMNA | |
| SCHEMBL3239627 | 0.91 | METTL3 (0.47) | METTL3PLA2G4AMRGPRX4 | |
| SCHEMBL1042843 | 0.91 | METTL3 (0.58) | METTL3P2RX7PLA2G4ACFDNTRK1 | |
| SCHEMBL1042844 | 0.91 | METTL3 (0.58) | METTL3P2RX7PLA2G4ACFDNTRK1 | |
| SCHEMBL3241874 | 0.91 | METTL3 (0.45) | METTL3CFDHIF1A | |
| SCHEMBL3243702 | 0.90 | METTL3 (0.43) | METTL3 | |
| SCHEMBL3242029 | 0.88 | METTL3 (0.43) | METTL3P2RX7CFD | |
| SCHEMBL3241571 | 0.88 | METTL3 (0.47) | METTL3P2RX7PLA2G4ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |