Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240307 | 0.91 | SLC22A12 (0.39) | SLC22A12GAAHTTLMNAALDH1A1 | |
| SCHEMBL3239189 | 0.89 | SLC22A12 (0.37) | SLC22A12GAAHTTLMNAALDH1A1 | |
| SCHEMBL1045975 | 0.88 | HTT (0.47) | SLC22A12GAAHTTLMNAALDH1A1 | |
| SCHEMBL3247056 | 0.87 | SLC22A12 (0.38) | SLC22A12GAAHTTLMNAALDH1A1 | |
| SCHEMBL3247016 | 0.87 | SLC22A12 (0.38) | SLC22A12GAAHTTLMNAALDH1A1 | |
| SCHEMBL3239774 | 0.87 | LMNA (0.46) | SLC22A12LMNAALDH1A1TP53MAPT | |
| SCHEMBL3246470 | 0.87 | SLC22A12 (0.41) | SLC22A12GAAHTTLMNAALDH1A1 | |
| SCHEMBL3245381 | 0.87 | ALDH1A1 (0.41) | SLC22A12HTTLMNAALDH1A1TP53 | |
| SCHEMBL3239637 | 0.86 | SLC22A12 (0.39) | SLC22A12GAAHTTLMNAALDH1A1 | |
| SCHEMBL3241585 | 0.86 | SLC22A12 (0.39) | SLC22A12GAAHTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |