Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240307 | 0.90 | SLC22A12 (0.39) | SLC22A12LMNAHTTALDH1A1GAA | |
| SCHEMBL3241719 | 0.89 | SLC22A12 (0.37) | SLC22A12LMNAHTTALDH1A1GAA | |
| SCHEMBL1076473 | 0.89 | LMNA (0.47) | SLC22A12LMNAHTTKDM4EALDH1A1 | |
| SCHEMBL3237310 | 0.86 | SLC22A12 (0.39) | SLC22A12LMNAHTTKDM4EALDH1A1 | |
| SCHEMBL3245381 | 0.86 | ALDH1A1 (0.41) | SLC22A12LMNAHTTKDM4EALDH1A1 | |
| SCHEMBL3242547 | 0.86 | SLC22A12 (0.38) | SLC22A12LMNAALDH1A1TP53POLB | |
| SCHEMBL3239892 | 0.86 | HTR6 (0.41) | SLC22A12LMNAALDH1A1TP53POLB | |
| SCHEMBL3235857 | 0.85 | SLC22A12 (0.38) | SLC22A12LMNAHTTALDH1A1GAA | |
| SCHEMBL3247125 | 0.85 | CNR2 (0.41) | SLC22A12LMNAALDH1A1TP53POLB | |
| SCHEMBL3241859 | 0.85 | SLC22A12 (0.40) | SLC22A12LMNAHTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |