Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11832466 | 0.87 | ADRA2B (0.33) | NPSR1POLBKMT2AAPEX1ATM | |
| SCHEMBL3245996 | 0.79 | PKM (0.35) | HDAC4NPSR1POLBKMT2AAPEX1 | |
| SCHEMBL8847086 | 0.75 | TAAR1 (0.38) | HDAC4LMNATSHR | |
| SCHEMBL11702282 | 0.70 | HTR1A (0.38) | L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL5866515 | 0.68 | CYP2D6 (0.46) | CYP2D6HDAC4KMT2APDK2CTSB | |
| SCHEMBL2729452 | 0.68 | HTR1A (0.38) | MAPTL3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL1667453 | 0.66 | HTR1A (0.39) | NPSR1KMT2AL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL23933927 | 0.64 | HDAC4 (0.49) | CYP2D6HDAC4PDK2MAPTGABRA1 | |
| SCHEMBL8123326 | 0.63 | CYP2D6 (0.45) | CYP2D6HDAC4POLBKMT2APDK2 | |
| SCHEMBL11165768 | 0.63 | SIGMAR1 (0.42) | KMT2AATMPDK2L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184364-B1 | COMB-SHAPED DIOL, WATER-SOLUBLE POLYURETHANE, AND USE THEREOF | MITSUI CHEMICALS INC (JP) | 2010-07-28 | — | — | EP | disclosed |
| US-6646093-B2 | Extruding auxiliary for cement materials, a mortar thickening agent, an underwater concrete thickening agent, a ceramics forming binder and a moisturizer for hair cosmetics; water and shape retention. | MITSUI CHEMICALS, INC. (JP) | 2003-11-11 | — | — | US | disclosed |
| US-6515050-B1 | An extruding auxiliary using the above novel water-soluble polyurethane; additive for underwater concrete | MITSUI CHEMICALS, INC. (JP) | 2003-02-04 | — | — | US | disclosed |
| US-20020045724-A1 | Water-souluble polyurthane having comb-shaped hydrophobic group and application thereof | MITSUI TAKEDA CHEMICALS, INC. (JP) | 2002-04-18 | — | — | US | disclosed |
| EP-1184364-A1 | COMB-SHAPED DIOL, WATER-SOLUBLE POLYURETHANE, AND USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2002-03-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045724-A1 | Water-souluble polyurthane having comb-shaped hydrophobic group and application thereof | BMI1, ASH2L, HAT1 | CYP2D6 3998/4885HDAC4 1729/4885NPSR1 3756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.