SCHEMBL3242480

SCHEMBL3242480

C=CC(=O)OCCNC(=O)Nc1ccc(P(=O)(O)O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.43
LMNA P02545 2/20 0.43
NPC1 O15118 1/20 0.43
HPGD P15428 1/20 0.43
MAPK1 P28482 1/20 0.43
NPSR1 Q6W5P4 2/20 0.38
GAA P10253 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
THRB P10828 1/20 0.37
CNR1 P21554 2/20 0.36
NAMPT P43490 1/20 0.36
MAPT P10636 3/20 0.35
ALDH1A1 P00352 6/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
POLB P06746 1/20 0.35
TSHR P16473 4/20 0.35
TP53 P04637 2/20 0.35
HIF1A Q16665 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1735862 0.84 RAB9A (0.47) RAB9ALMNANPC1HPGDMAPK1
SCHEMBL3253043 0.83 GAA (0.54) RAB9ALMNANPC1HPGDMAPK1
SCHEMBL10093589 0.83 CNR1 (0.48) RAB9ALMNANPC1HPGDMAPK1
SCHEMBL3252507 0.82 NPSR1 (0.53) RAB9ALMNANPC1HPGDMAPK1
SCHEMBL4340532 0.82 EPHX2 (0.48) RAB9ALMNANPC1HPGDMAPK1
SCHEMBL3247026 0.81 CNR1 (0.41) RAB9ALMNANPC1HPGDMAPK1
SCHEMBL13899143 0.80 NPSR1 (0.51) LMNANPSR1GAASMN1; SMN2THRB
SCHEMBL3252353 0.80 NPC1 (0.43) RAB9ALMNANPC1HPGDMAPK1
SCHEMBL1734785 0.79 CA2 (0.55) NAMPTMEN1KMT2AL3MBTL1KDM4E
SCHEMBL21950052 0.79 TGM2 (0.55) RAB9ALMNANPC1HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3521927-B1 POSITIVE WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MANUFACTURING THE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2021-10-27 EP disclosed
US-10649337-B2 Positive type lithographic printing plate precursor, method of producing same, and method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2020-05-12 US disclosed
EP-3521927-A1 POSITIVE PLANOGRAPHIC PRINTING ORIGINAL PLATE AND METHOD FOR MANUFACTURING SAME, AND METHOD FOR PRODUCING PLANOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2019-08-07 EP disclosed
US-20190212652-A1 POSITIVE TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PRODUCING SAME, AND METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2019-07-11 US disclosed
EP-1705004-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2013-09-25 EP disclosed
EP-1136886-B1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORP (JP) 2010-05-19 EP disclosed
US-20090246693-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-1705004-A1 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2006-09-27 EP disclosed
US-6517987-B2 Mixture of 1,2-naphthoquinone-2-diazide-5-sulfonic acid and polymer FUJI PHOTO FILM CO., LTD. (JP) 2003-02-11 US disclosed
US-20010041299-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate FUJIFILM CORPORATION (JP) 2001-11-15 US disclosed
EP-1136886-A1 Positive-working presensitized plate useful for preparing a lithographic printing plate Fuji Photo Film Co., Ltd. (JP) 2001-09-26 EP disclosed