Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 12/20 | 0.47 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3242721 | 0.94 | MAPT (0.48) | ALDH1A1KDM4EKMT2AL3MBTL1ROCK2 | |
| SCHEMBL3131955 | 0.84 | ROCK2 (0.66) | ROCK2ROCK1 | |
| SCHEMBL3242410 | 0.84 | ROCK2 (0.49) | ROCK2NPC1RAB9AROCK1CYP2C9 | |
| SCHEMBL3249259 | 0.80 | ROCK2 (0.58) | ALDH1A1KDM4EKMT2ANPSR1L3MBTL1 | |
| SCHEMBL3124817 | 0.79 | ROCK2 (0.64) | KMT2AROCK2ROCK1CYP2C9CDC42BPA | |
| SCHEMBL3247042 | 0.79 | ROCK2 (0.56) | ALDH1A1KDM4EKMT2ANPSR1L3MBTL1 | |
| SCHEMBL3247286 | 0.79 | ROCK2 (0.59) | ALDH1A1KDM4EKMT2ANPSR1L3MBTL1 | |
| SCHEMBL3241492 | 0.78 | ROCK2 (0.55) | ALDH1A1KDM4EKMT2ANPSR1L3MBTL1 | |
| SCHEMBL3245748 | 0.77 | ROCK2 (0.70) | ROCK2ROCK1CDC42BPA | |
| SCHEMBL1986880 | 0.76 | ROCK2 (0.75) | ROCK2ROCK1CDC42BPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | claimed |
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |