Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243218 | 1.00 | NAMPT (0.49) | NAMPTL3MBTL1MIFNPC1RAB9A | |
| SCHEMBL3180689 | 0.84 | L3MBTL1 (0.61) | NAMPTL3MBTL1RECQLGAAMAPT | |
| SCHEMBL13181773 | 0.84 | GLS (0.47) | NAMPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12206558 | 0.84 | GLS (0.47) | NAMPTL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL208544 | 0.84 | EPHX2 (0.57) | NAMPTL3MBTL1MIFNPC1RAB9A | |
| SCHEMBL19853209 | 0.82 | L3MBTL1 (0.51) | NAMPTL3MBTL1MIFNPC1RAB9A | |
| SCHEMBL19373096 | 0.81 | L3MBTL1 (0.52) | NAMPTL3MBTL1RECQLGAAMAPT | |
| SCHEMBL2526083 | 0.79 | RAB9A (0.45) | MIFNPC1RAB9ARECQLSMN1; SMN2 | |
| SCHEMBL12206615 | 0.79 | KDM4E (0.42) | MIFNPC1RAB9ARECQLSMN1; SMN2 | |
| SCHEMBL12206651 | 0.79 | KDM4E (0.42) | MIFNPC1RAB9ARECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997813-B1 | SUBSTITUTED ISOXAZOLINE COMPOUND AND PEST CONTROL AGENT | NISSAN CHEMICAL IND LTD (JP) | 2010-05-05 | — | — | EP | disclosed |