Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | CTSC | P53634 | 2/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | BCR | P11274 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4391246 | 0.74 | TYK2 (0.45) | SCN5ASYKCA12CA9ABL1 | |
| SCHEMBL2324450 | 0.73 | TEK (0.52) | TEKCTSCSCN5ACA12CA9 | |
| SCHEMBL2324455 | 0.73 | TEK (0.55) | TEKCTSCPLK1SCN5ACA12 | |
| SCHEMBL1227164 | 0.73 | CHRM5 (0.52) | TEKSCN5ACA12CA9ABL1 | |
| SCHEMBL3246352 | 0.72 | CTSC (0.53) | CTSCSYKKIF11 | |
| SCHEMBL3235251 | 0.70 | NRP1 (0.45) | TEKKCNH2SCN10A | |
| SCHEMBL29501823 | 0.70 | TRPA1 (0.53) | CTSCSCN5AABL1BCRTRPA1 | |
| SCHEMBL28403016 | 0.70 | TRPA1 (0.53) | CTSCSCN5AABL1BCRTRPA1 | |
| SCHEMBL17157363 | 0.70 | SCN5A (0.48) | TEKSCN5ACA12CA9SCN9A | |
| SCHEMBL3243119 | 0.69 | CDK8 (0.46) | TEKCA12CA9ABL1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | claimed |
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |