Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 7/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 3/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6266948 | 0.85 | ALOX5AP (0.39) | TYK2SCN5ANPY5RABL1SCN10A | |
| SCHEMBL6762808 | 0.82 | ALOX5AP (0.39) | TYK2SCN5ACA12CA9NPY5R | |
| SCHEMBL20654333 | 0.77 | NPC1 (0.59) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL6270519 | 0.76 | SCN5A (0.39) | TYK2SCN5ASCN1ASCN2AALOX5AP | |
| SCHEMBL4389561 | 0.76 | NPC1 (0.58) | ALOX5APFEN1KDM4ENPC1ALDH1A1 | |
| SCHEMBL7685872 | 0.75 | ALDH1A1 (0.48) | SCN2AALDH1A1GAA | |
| SCHEMBL3243263 | 0.74 | TEK (0.46) | SCN5ACA12CA9NPY5RABL1 | |
| SCHEMBL1230049 | 0.74 | SCN5A (0.48) | SCN5ACA12CA9NPY5RSCN10A | |
| SCHEMBL1227164 | 0.74 | CHRM5 (0.52) | SCN5ACA12CA9NPY5RABL1 | |
| SCHEMBL16215338 | 0.74 | GABBR2 (0.49) | SCN5ACA12CA9SCN10AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175407-B1 | PESTICIDAL PYRIMIDINE-DERIVATIVES | NOVARTIS AG (CH) | 2009-12-09 | — | — | EP | disclosed |
| US-6686469-B2 | TREATMENT FOR PLANT PROPAGATION MATERIAL FOR PARASITICIDES | NOVARTIS ANIMAL HEALTH US, INC. | 2004-02-03 | — | — | US | disclosed |
| US-20030004347-A1 | Pesticidal pyrimidine-derivatives | NOVARTIS ANIMAL HEALTH US, INC. | 2003-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030004347-A1 | Pesticidal pyrimidine-derivatives | CTRC, HCN1, DDT | TYK2 2985/4885SCN5A 1433/4885CA12 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.