Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 5/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3243595 | 0.72 | VNN1 (0.43) | CYP3A4CYP2C9CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL9661853 | 0.70 | KCNA5 (0.44) | CYP3A4CYP2C9CYP1A2CYP2C19GBA1 | |
| SCHEMBL9661857 | 0.70 | KCNA5 (0.44) | CYP3A4CYP2C9CYP1A2CYP2C19GBA1 | |
| SCHEMBL5529415 | 0.68 | CYP19A1 (0.43) | CYP2D6KCNA5KCNN4CHRM2 | |
| SCHEMBL7823617 | 0.67 | VNN1 (0.46) | CYP3A4CYP2C9CYP1A2CYP2C19VNN1 | |
| SCHEMBL7823614 | 0.67 | VNN1 (0.46) | CYP3A4CYP2C9CYP1A2CYP2C19VNN1 | |
| SCHEMBL9804889 | 0.67 | CYP1A2 (0.37) | CYP3A4CYP2C9CYP1A2CYP2C19HRH1 | |
| SCHEMBL8309619 | 0.64 | VNN1 (0.38) | CYP3A4CYP2C9CYP1A2CYP2C19VNN1 | |
| SCHEMBL9302450 | 0.63 | VNN1 (0.42) | CYP3A4CYP2C9CYP1A2CYP2C19VNN1 | |
| SCHEMBL9302445 | 0.63 | VNN1 (0.42) | CYP3A4CYP2C9CYP1A2CYP2C19VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070225287-A1 | Substituted Arylpyrazines | YOON TAEYOUNG | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070225287-A1 | Substituted Arylpyrazines | CRHR1, CRHR2, CRH | CYP3A4 1626/4885CYP2C9 2589/4885CYP1A2 658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.