Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 2/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19064206 | 0.91 | BRPF1 (0.32) | SLC6A1SMN1; SMN2SLC6A11LMNASLC6A13 | |
| SCHEMBL27685321 | 0.83 | CTSK (0.39) | SMN1; SMN2LMNAKDM4EMAPTKMT2A | |
| SCHEMBL25281562 | 0.81 | POLB (0.35) | SMN1; SMN2LMNAMAPTKMT2AATM | |
| SCHEMBL27772357 | 0.81 | CPN1 (0.42) | CPN1CPB2SLC6A1SMN1; SMN2SLC6A11 | |
| SCHEMBL6050056 | 0.79 | CPN1 (0.45) | CPN1CPB2SLC6A1SMN1; SMN2SLC6A11 | |
| SCHEMBL6709446 | 0.77 | SMN1; SMN2 (0.43) | CPN1CPB2SLC6A1SMN1; SMN2SLC6A11 | |
| SCHEMBL6443600 | 0.77 | SMN1; SMN2 (0.43) | CPN1CPB2SLC6A1SMN1; SMN2SLC6A11 | |
| SCHEMBL28202522 | 0.74 | CPN1 (0.41) | CPN1CPB2SLC6A1SMN1; SMN2SLC6A11 | |
| SCHEMBL17513413 | 0.73 | SLC6A1 (0.37) | SLC6A1SMN1; SMN2SLC6A11TSHRLMNA | |
| SCHEMBL3698542 | 0.73 | SLC6A1 (0.37) | SLC6A1SMN1; SMN2SLC6A11TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2182809-A1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | Helicon Therapeutics, Inc. (US) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009029632-A1 | THERAPEUTIC ISOXAZOLE COMPOUNDS | HELICON THERAPEUTICS, INC. (US) | 2009-03-05 | — | — | WO | disclosed |