Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 2/20 | 0.47 |
| ▸ | CTSC | P53634 | 2/20 | 0.46 |
| ▸ | GALR2 | O43603 | 2/20 | 0.45 |
| ▸ | GALR1 | P47211 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | ITK | Q08881 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22431578 | 0.85 | SYK (0.60) | SYKIGF1RCTSCEPHX2EGFR | |
| Hydrochloric Acid SCHEMBL22405020 | 0.84 | SYK (0.59) | SYKIGF1RCTSCEPHX2EGFR | |
| SCHEMBL3244704 | 0.81 | SYK (0.52) | SYKIGF1RCTSCGALR2GALR1 | |
| SCHEMBL3246352 | 0.77 | CTSC (0.53) | SYKIGF1RCTSCGALR2GALR1 | |
| SCHEMBL3242077 | 0.76 | CTSC (0.47) | SYKIGF1RCTSCGALR2GALR1 | |
| SCHEMBL3234950 | 0.76 | CTSC (0.52) | SYKIGF1RCTSCGALR2GALR1 | |
| SCHEMBL3247690 | 0.75 | IGF1R (0.53) | SYKIGF1RCTSCGALR2GALR1 | |
| SCHEMBL28459184 | 0.74 | SYK (0.60) | SYKIGF1RCTSCEPHX2EGFR | |
| SCHEMBL21088768 | 0.74 | SYK (0.46) | SYKIGF1RCTSCGALR2GALR1 | |
| SCHEMBL3242880 | 0.74 | BRAF (0.54) | SYKCTSCABL1BCREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010057833-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-05-27 | — | — | WO | disclosed |