Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469289 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTBCAT1TSHRKMT2A | |
| SCHEMBL15062217 | 0.82 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTBCAT1TSHRKMT2A | |
| SCHEMBL9711936 | 0.79 | CA2 (0.57) | SMN1; SMN2TSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL3828442 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2HTTBCAT1TSHRHTR6 | |
| SCHEMBL7266697 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2HTTBCAT1TSHRKMT2A | |
| SCHEMBL9043625 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2HTTBCAT1TSHRKMT2A | |
| SCHEMBL9732594 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2HTTBCAT1TSHRKMT2A | |
| SCHEMBL11107252 | 0.78 | GAA (0.54) | SMN1; SMN2HTTKMT2AALDH1A1LMNA | |
| SCHEMBL12588794 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTBCAT1TSHRKMT2A | |
| (Phenylsulfonyl)Benzene SCHEMBL2381369 | 0.77 | HTR6 (0.74) | SMN1; SMN2BCAT1TSHRKMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127580-A | MULTISTAGE | PARCOR (FR) | 1978-11-28 | — | — | US | claimed |
| CN-118598780-A | Aggregation-induced emission naphthyl benzenesulfonyl ethanone and preparation thereof | 内蒙古工业大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-110036022-A | Antibody-coupled cyclic peptide tyrosine compounds as modulators of neuropeptide Y receptors | 詹森药业有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-103841991-B | Diagnosis and the method for the treatment of blood vessel related maculopathy and its symptom | 犹他大学研究基金会 | 2018-03-27 | — | — | CN | disclosed |
| CN-106687128-A | Compositions and methods for treating metabolic disorders | NGM生物制药有限公司 | 2017-05-17 | — | — | CN | disclosed |
| CN-102361857-A | Novel cyclic benzimidazole derivatives useful anti-diabetic agents | MERCK SHARP & DOHME | 2012-02-22 | — | — | CN | disclosed |
| CN-102271511-A | Novel cyclic benzimidazole derivatives useful anti-diabetic agents | — | 2011-12-07 | — | — | CN | disclosed |
| EP-1167366-B1 | AMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-7199139-B2 | Medicinal compositions containing diuretic and insulin resistance-improving agent | SANKYO COMPANY, LIMITED (JP) | 2007-04-03 | — | — | US | disclosed |
| EP-1354602-B1 | MEDICINAL COMPOSITIONS CONTAINING DIURETIC AND INSULIN RESISTANCE-IMPROVING AGENT | SANKYO CO (JP) | 2006-10-04 | — | — | EP | disclosed |
| EP-1354602-A1 | MEDICINAL COMPOSITIONS CONTAINING DIURETIC AND INSULIN RESISTANCE-IMPROVING AGENT | Sankyo Company, Limited (JP) | 2003-10-22 | — | — | EP | disclosed |
| US-6596751-B2 | An insulin resistance improving agent, hypoglycemic agent, immunoregulatory agent, aldose reductase inhibitor, 5-lipoxygenase inhibitor, peroxidized lipid production suppressor, PPAR. activator, leukotriene antagonist, adipose | SANKYO COMPANY LIMITED (JP) | 2003-07-22 | — | — | US | disclosed |
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-20030078426-A1 | Amine derivative compounds | SANKYO COMPANY, LIMITED (JP) | 2003-04-24 | — | — | US | disclosed |
| US-20030069294-A1 | Alpha-substituted carboxylic acid derivatives | SANKYO COMPANY, LIMITED (JP) | 2003-04-10 | — | — | US | disclosed |
| EP-1167366-A1 | AMINE DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
| EP-1167357-A1 | ALPHA-SUBSTITUTED CARBOXYLIC ACID DERIVATIVES | Sankyo Company, Limited (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-5026740-A | For transparent or pigmented mixtures | FRATELLI LAMBERTI S.P.A. (IT) | 1991-06-25 | — | — | US | disclosed |
| EP-0192967-B1 | SULPHURATED DERIVATIVES OF AROMATIC-ALIPHATIC AND ALIPHATIC KETONES AS POLYMERISATION PHOTOINITIATORS | FRATELLI LAMBERTI S.p.A. (IT) | 1990-08-01 | — | — | EP | disclosed |
| EP-0192967-A1 | Sulphurated derivatives of aromatic-aliphatic and aliphatic ketones as polymerisation photoinitiators | FRATELLI LAMBERTI S.p.A. (IT) | 1986-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069294-A1 | Alpha-substituted carboxylic acid derivatives | SLC5A1, SLC2A1, GPR119 | SMN1; SMN2 2259/4885HTT 4507/4885BCAT1 20/4885 |
| US-20030078426-A1 | Amine derivative compounds | H1-10, APOB, PRMT1 | SMN1; SMN2 3933/4885HTT 3024/4885BCAT1 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.