Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533711 | 0.94 | — | — | |
| Methyl Alcohol SCHEMBL9025055 | 0.92 | KMT2A (0.50) | MEN1KMT2ACYP1A2GAAMGAM | |
| Methylene Chloride SCHEMBL7854039 | 0.88 | KMT2A (0.47) | MEN1KMT2ACYP1A2GAAMGAM | |
| Chloroform SCHEMBL8572106 | 0.86 | KMT2A (0.46) | MEN1KMT2ACYP1A2GAAMGAM | |
| Hexane SCHEMBL6533487 | 0.86 | DGKA (0.47) | MEN1KMT2ACYP1A2GAAMGAM | |
| SCHEMBL9311598 | 0.82 | CYP1A2 (0.55) | MEN1KMT2ACYP1A2GAAMGAM | |
| Succinic Acid Diethyl Ester SCHEMBL27646294 | 0.80 | GAA (0.57) | CYP1A2GAAMGAMSIMGAM2 | |
| Ammonia Solution, Strong SCHEMBL27604884 | 0.80 | CYP1A2 (0.53) | MEN1KMT2ACYP1A2GAAMGAM | |
| SCHEMBL6670792 | 0.80 | CYP1A2 (0.53) | MEN1KMT2ACYP1A2GAAMGAM | |
| Toluene SCHEMBL6619389 | 0.79 | SMN1; SMN2 (0.48) | MEN1KMT2AALDH1A1POLBCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450476-B2 | Making drospirenone; chemical intermediates e.g. carbethoxy-drospirenone; industrial scale, safe (no chromium catalyst), meets purity requirements | RICHTER GEDEON NYRT. (HU) | 2013-05-28 | — | — | US | claimed |
| US-8309712-B2 | Synthesis of drospirenone in only eight steps; claimed intermediates; readily available raw materials; simple crystallization purification; no hazardous materials; yield | RICHTER GEDEON NYRT. (HU) | 2012-11-13 | — | — | US | claimed |
| CN-101061132-B | Process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-dimethylene-17 alpha-pregn-4-en-3-one-21-carboxylic acid gamma-lactone and key intermediates used in the process | RICHTER GEDEON VEGYESZET | 2011-03-30 | — | — | CN | claimed |
| CN-101061133-B | Industrial process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-dimethylene-3-oxo-17 alpha pregn-4-ene-21-hydroxyacid gamma-lactone and key intermediates used in the process | RICHTER GEDEON VEGYZET | 2011-01-26 | — | — | CN | claimed |
| EP-1817326-B1 | INDUSTRIAL PROCESS FOR THE PREPERATION OF 17-HYDROXY -6 BETA, 7-BETA, 15-BETA, 16-BETA-BISMETHYLENE-3-OXO 17-ALPHA PREGN-4-ENE-21-CARBOXYLIC ACID GAMMA-LACTONE AND KEY INTERMEDIATES FOR THIS PROCESS | RICHTER GEDEON NYRT (HU) | 2010-05-19 | — | — | EP | claimed |
| US-20080200668-A1 | Industrial Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene-3-Oxo-17Alpha-Pregn-4-Ene-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2008-08-21 | — | — | US | claimed |
| US-20080194812-A1 | Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene- 17Alpha-Pregn-4-Ene-3-One-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2008-08-14 | — | — | US | claimed |
| CN-101061133-A | Industrial process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-dimethylene-3-oxo-17 alpha pregn-4-ene-21-carboxylic acid gamma-lactone and key intermediates used in the process | RICHTER GEDEON VEGYZETI GYAR R (HU) | 2007-10-24 | — | — | CN | claimed |
| CN-101061132-A | Process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-dimethylene-17 alpha-pregn-4-en-3-one-21-carboxylic acid gamma-lactone and key intermediates used in the process | RICHTER GEDEON VEGYZETI GYAR R (HU) | 2007-10-24 | — | — | CN | claimed |
| EP-1817326-A1 | INDUSTRIAL PROCESS FOR THE PREPERATION OF 17-HYDROXY -6 BETA, 7-BETA, 15-BETA, 16-BETA-BISMETHYLENE-3-OXO 17-ALPHA PREGN-4-ENE-21-CARBOXYLIC ACID GAMMA-LACTONE AND KEY INTERMEDIATES FOR THIS PROCESS | Richter Gedeon Vegy Szeti Gy R Rt. (HU) | 2007-08-15 | — | — | EP | claimed |
| WO-2006059167-A1 | INDUSTRIAL PROCESS FOR THE PREPARATION OF 17-HYDROXY-6β,7β;15β,16β-BISMETHYLENE-3-OXO-17α-PREGN-4-ENE-21-CARBOXYLIC ACID Ϝ-LACTONE AND KEY-INTERMEDIATES FOR THIS PROCESS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-06-08 | — | — | WO | claimed |
| US-8309712-B2 | Synthesis of drospirenone in only eight steps; claimed intermediates; readily available raw materials; simple crystallization purification; no hazardous materials; yield | RICHTER GEDEON NYRT. (HU) | 2012-11-13 | — | — | US | disclosed |
| CN-101061133-B | Industrial process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-dimethylene-3-oxo-17 alpha pregn-4-ene-21-hydroxyacid gamma-lactone and key intermediates used in the process | RICHTER GEDEON VEGYZET | 2011-01-26 | — | — | CN | disclosed |
| EP-1817326-B1 | INDUSTRIAL PROCESS FOR THE PREPERATION OF 17-HYDROXY -6 BETA, 7-BETA, 15-BETA, 16-BETA-BISMETHYLENE-3-OXO 17-ALPHA PREGN-4-ENE-21-CARBOXYLIC ACID GAMMA-LACTONE AND KEY INTERMEDIATES FOR THIS PROCESS | RICHTER GEDEON NYRT (HU) | 2010-05-19 | — | — | EP | disclosed |
| US-20080200668-A1 | Industrial Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene-3-Oxo-17Alpha-Pregn-4-Ene-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2008-08-21 | — | — | US | disclosed |
| CN-101061133-A | Industrial process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta-dimethylene-3-oxo-17 alpha pregn-4-ene-21-carboxylic acid gamma-lactone and key intermediates used in the process | RICHTER GEDEON VEGYZETI GYAR R (HU) | 2007-10-24 | — | — | CN | disclosed |
| EP-1817326-A1 | INDUSTRIAL PROCESS FOR THE PREPERATION OF 17-HYDROXY -6 BETA, 7-BETA, 15-BETA, 16-BETA-BISMETHYLENE-3-OXO 17-ALPHA PREGN-4-ENE-21-CARBOXYLIC ACID GAMMA-LACTONE AND KEY INTERMEDIATES FOR THIS PROCESS | Richter Gedeon Vegy Szeti Gy R Rt. (HU) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006059167-A1 | INDUSTRIAL PROCESS FOR THE PREPARATION OF 17-HYDROXY-6β,7β;15β,16β-BISMETHYLENE-3-OXO-17α-PREGN-4-ENE-21-CARBOXYLIC ACID Ϝ-LACTONE AND KEY-INTERMEDIATES FOR THIS PROCESS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200668-A1 | Industrial Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene-3-Oxo-17Alpha-Pregn-4-Ene-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process | HSD17B7, CYP17A1, HSD17B11 | MEN1 1419/4885KMT2A 3034/4885CYP1A2 52/4885 |
| US-20080194812-A1 | Process for the Preparation of 17-Hydroxy-6Beta, 7Beta; 15Beta, 16Beta-Bismethylene- 17Alpha-Pregn-4-Ene-3-One-21-Carboxylic Acid Y-Lactone and Key Intermediates for this Process | CYP17A1, HSD17B7, HSD17B11 | MEN1 1301/4885KMT2A 2932/4885CYP1A2 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.