Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533711 | 0.92 | — | — | |
| Methyl Alcohol SCHEMBL9025055 | 0.90 | KMT2A (0.50) | CYP1A2MEN1KMT2ATSHRMGAM | |
| SCHEMBL8712386 | 0.87 | NAAA (0.55) | DGKAPAMTSHRDNM1HTR2C | |
| Cyclohexane SCHEMBL3245595 | 0.86 | MEN1 (0.47) | CYP1A2MEN1KMT2ATSHRMGAM | |
| Methylene Chloride SCHEMBL7854039 | 0.86 | KMT2A (0.47) | CYP1A2MEN1KMT2ATSHRMGAM | |
| SCHEMBL10410250 | 0.86 | DGKA (0.40) | DGKACYP1A2MEN1KMT2APAM | |
| SCHEMBL16986082 | 0.85 | DGKA (0.52) | DGKAPAMTSHRMAPTALDH1A1 | |
| Chloroform SCHEMBL8572106 | 0.85 | KMT2A (0.46) | CYP1A2MEN1KMT2ATSHRMGAM | |
| SCHEMBL9311598 | 0.84 | CYP1A2 (0.55) | DGKACYP1A2MEN1KMT2ATSHR | |
| SCHEMBL6670792 | 0.82 | CYP1A2 (0.53) | DGKACYP1A2MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170342086-A1 | Compounds and methods for the treatment of drug resistance in cancer cells against paclitaxel | KUMAR AJAY (US) | 2017-11-30 | — | — | US | claimed |
| CN-104062367-A | Method for directly analyzing content of 1,5-naphthalene diisocyanate by normal-phase high performance liquid chromatography | UNIV XIANGTAN | 2014-09-24 | — | — | CN | claimed |
| EP-1569617-A1 | WATER STABILIZED MEDICINAL AEROSOL FORMULATION RELATED APPLICATIONS | Kos Life Sciences, Inc. (US) | 2005-09-07 | — | — | EP | claimed |
| WO-2004022035-A1 | WATER STABILIZED MEDICINAL AEROSOL FORMULATION RELATED APPLICATIONS | KOS PHARMACEUTICALS, INC. (US) | 2004-03-18 | — | — | WO | claimed |
| CN-111164091-A | Oligonucleotide compositions and methods of use thereof | 波涛生命科学有限公司 | 2020-05-15 | — | — | CN | disclosed |
| CN-111050806-A | Oligonucleotide compositions and methods of use thereof | 波涛生命科学有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-111051281-A | Compounds, compositions and methods for synthesis | 波涛生命科学有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-110997692-A | Oligonucleotide compositions and methods of use thereof | 波涛生命科学有限公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-104062367-A | Method for directly analyzing content of 1,5-naphthalene diisocyanate by normal-phase high performance liquid chromatography | UNIV XIANGTAN | 2014-09-24 | — | — | CN | disclosed |
| WO-1998038185-A9 | DITHIANE-BASED COUPLING PROCEDURES AND PRODUCTS THEREOF | — | 1999-02-11 | — | — | WO | disclosed |
| WO-1998038185-A1 | DITHIANE-BASED COUPLING PROCEDURES AND PRODUCTS THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1998-09-03 | — | — | WO | disclosed |
| US-5399714-A | Process for the preparation of substituted indoles | CIBA-GEIGY CORPORATION (US) | 1995-03-21 | — | — | US | disclosed |
| US-5260214-A | Aureobasidium pullulans which produces antibiotic R106 | TAKARA SHUZO CO. (JP) | 1993-11-09 | — | — | US | disclosed |
| EP-0352092-B1 | Novel antibiotics R106 | TAKARA SHUZO CO (JP) | 1993-10-27 | — | — | EP | disclosed |
| US-5158876-A | Fungicides | TAKARA SHUZO CO., LTD. (JP) | 1992-10-27 | — | — | US | disclosed |
| US-5057493-A | Cyclic peptides, also fungicides | TAKARA SHUZO CO., LTD. (JP) | 1991-10-15 | — | — | US | disclosed |
| US-4795748-A | Antibacterial 7-oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1989-01-03 | — | — | US | disclosed |
| US-4771057-A | TREATMENT OF ANGINA, ARRHYTHMIAS, CEREBRALVASCULAR DISEASE AND HYPERTENSION | UNIVERSITY OF ALBERTA (CA) | 1988-09-13 | — | — | US | disclosed |
| EP-0170028-A1 | Antibacterial 7-oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1986-02-05 | — | — | EP | disclosed |
| US-4171365-A | Antiviral aryloxyalkylpyrazoles | STERLING DRUG INC. (US) | 1979-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342086-A1 | Compounds and methods for the treatment of drug resistance in cancer cells against paclitaxel | MCL1, PIM1, ABCC1 | DGKA 317/4885CYP1A2 4656/4885MEN1 3803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.