Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3236491 | 0.86 | SMN1; SMN2 (0.46) | HRH3ALOX5TAAR1KIF11CYP17A1 | |
| SCHEMBL3233011 | 0.86 | EPHX2 (0.52) | PRMT6CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL3243661 | 0.84 | PSMB5 (0.42) | PRMT6TAAR1AOC3 | |
| SCHEMBL3245933 | 0.83 | CLK4 (0.40) | KDM4ESMN1; SMN2 | |
| SCHEMBL20031290 | 0.80 | PRKCI (0.61) | PRKCIPRMT6ABHD6MGLLHRH3 | |
| Hydrochloric Acid SCHEMBL7975188 | 0.76 | AOC3 (0.55) | PRMT6HRH3TAAR1CYP3A4AOC3 | |
| SCHEMBL15263998 | 0.75 | ABHD6 (0.69) | PRKCIPRMT6ABHD6MGLLUSP30 | |
| SCHEMBL3239914 | 0.74 | CHRNB2 (0.67) | KDM4E | |
| SCHEMBL3242409 | 0.74 | ALDH1A1 (0.54) | PRMT6HRH3TAAR1CYP3A4AOC3 | |
| SCHEMBL30093206 | 0.72 | KDM4E (0.53) | HRH3ALOX5CYP3A4KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144733-A1 | Compounds, compositions and methods comprising heteroaromatic derivatives | INSTITUTE FOR ONEWORLD HEALTH | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144733-A1 | Compounds, compositions and methods comprising heteroaromatic derivatives | CFTR, PKD1, PKD2 | PRKCI 302/4885PRMT6 3989/4885ABHD6 2437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.