Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044528 | 0.91 | MAPT (0.41) | SLC22A12MAPTTP53POLBCNR2 | |
| SCHEMBL3245040 | 0.91 | MTNR1A (0.38) | SLC22A12MAPTTP53POLBCNR2 | |
| SCHEMBL3247125 | 0.88 | CNR2 (0.41) | SLC22A12MAPTTP53POLBCNR2 | |
| SCHEMBL3245321 | 0.86 | CNR2 (0.45) | SLC22A12MAPTTP53POLBCNR2 | |
| SCHEMBL3245381 | 0.86 | ALDH1A1 (0.41) | SLC22A12MAPTTP53POLBALDH1A1 | |
| SCHEMBL3235184 | 0.86 | SLC22A12 (0.36) | SLC22A12MAPTTP53POLBCNR2 | |
| SCHEMBL3239637 | 0.85 | SLC22A12 (0.39) | SLC22A12MAPTTP53POLBCNR2 | |
| SCHEMBL3241585 | 0.85 | SLC22A12 (0.39) | SLC22A12MAPTTP53POLBCNR2 | |
| SCHEMBL3247047 | 0.85 | CNR1 (0.39) | SLC22A12MAPTTP53POLBCNR2 | |
| SCHEMBL3243264 | 0.84 | SLC22A12 (0.40) | SLC22A12CNR2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564210-B9 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2010-03-31 | — | — | EP | claimed |
| EP-1564210-B1 | 4-OXOQUINOLINE COMPOUNDS AND UTILIZATION THEREOF AS HIV INTEGRASE INHIBITORS | JAPAN TOBACCO INC (JP) | 2009-09-16 | — | — | EP | claimed |